Novo Nordisk A/S (NOVOB) Earnings Call Transcript & Summary

November 30, 2020

Nasdaq Copenhagen DK Health Care Pharmaceuticals special 91 min

Earnings Call Speaker Segments

Operator

operator
#1

Hello, and welcome to the Novo Nordisk A/S conference call. [Operator Instructions] Today, I'm pleased to present Lars Fruergaard Jørgensen, CEO. Please go ahead with your meeting.

Lars Jørgensen

executive
#2

Thank you very much, and welcome to this conference call regarding our approach to sustainability. With me today, I have Camilla Sylvest, Executive Vice President and Head of Commercial Strategy and Corporate Affairs. I also have Henrik Wulff, Executive Vice President of Product Supply, Quality and IT. I also have Monique Carter, Executive Vice President of People and Organization. And finally, I have Karsten Munk Knudsen, Executive Vice President and Chief Financial Officer. Please turn to Slide 2. We will to today be making forward-looking statements, and I have to remind you that such forward-looking statements would include risks and uncertainties. So please look at Slide 2 and also make reference to our quarterly and annual reports for further disclosure on forward-looking statements. Please turn to Slide 3. In November 2019, Novo Nordisk launched our new approach to guidance based on our strategic aspirations 2025. They include 4 quadrants. And today, we will be focusing on the first quadrant, which is purpose and sustainability, where we have 3 elements. One linked to our social responsibility, one linked to our environmental responsibility and then one linked to what it means to be a sustainable workplace. If you look at Slide 4, you will see that for many years, Novo Nordisk has been focused on these sustainability factors, and we have an extensive experience in running a sustainable company. This goes back to our founders mentality of having focus on science and humanitarian purposes as well as creating good conditions for our employees. In the late 1990s, we formulated what we call the Triple Bottom Line principle, and you can see on the timeline here on Page 4 that we have achieved a number of milestones in this regard. I'll just highlight a few, and then we will join today, dive deeper into many of these. In 2001, we launched the World Diabetes Foundation. In 2002, all Novo Nordisk manufacturing sites were ISO 14001 certified. This is the environmental certification. In 2004, we made our first integrated report incorporating finance and sustainability reporting. And this was also the year where we included the Triple Bottom Line business approach into our articles of association. In the following years, there were a number of programs linked to changing diabetes working with programs to really improve diabetes care. and this led up to a new social responsibility strategy to defeat diabetes announced this year. In the recent years, we have also made strong progress in terms of our environmental responsibility, and this year, we achieved one of our targets of supplying -- of running all our global manufacturing sites based on 100% renewable power. We will throughout this meeting, go into more details on many of these initiatives. Please turn to Slide 5. In Novo Nordisk, we believe that long-term value to society is driven by a strong sense of purpose and being a responsible business. This is really well supported by our ownership structure where we have, as you know, a combination of shares owned by our Novo Nordisk Foundation and obviously, also institutional and private investors. This brings a good combination of both a long-term focus, while also making sure that we have agile response to changing circumstances. Since 2004, as I mentioned, we have had our financial, environmental and social responsibility anchored in the articles of association based on this Triple Line business principle, where we are responsible for our social responsibility, our environmental responsibility and also our financial responsibility, all aimed at achieving our purpose. And these business contracts are guided by what we call the Novo Nordisk Way, which we'll also introduce a bit later. Please turn to Slide 6. We keep raising our ambition levels within these 3 dimensions. And examples are our recent defeat diabetes, social responsibility and the launch last year of our Circular for Zero in environmental strategy. We also seek inspiration from the various sustainability indexes and standards, while there's not one uniform standard, we believe we can learn from many of them. When you look at our ratings, we believe our approach is acknowledged by a number of these ranking agencies, and we are pleased with our standing in this regard. Please turn to Slide 7. Here we have the agenda for the remainder of today. We'll start out by looking at our environmental responsibility and I've mentioned Circular for Zero strategy. And that will be done by Camilla Sylvest and Henrik Wulff. And after their presentation, there will be 10 minutes for Q&As on our environmental responsibility activities. Following that, we will dive into our social responsibility to defeat diabetes and what we mean is important in terms of being a sustainable workplace. And that will be covered by Camilla Sylvest and Monique Carter and, again, followed by 10 minutes for Q&A on social responsibility. We will end up by a section on corporate governance and what it means to have a responsible business conduct, and that will be covered by Karsten Munk Knudsen and again, followed by a Q&A session on that specific topic and any other topic you might have. So with that, I'll hand over to Camilla.

Camilla Sylvest

executive
#3

Thank you, Lars, and please turn to Slide 8. As part of our commitment to science-based targets, we have developed our environmental strategy, Circular for Zero and Circular for Zero aspire to have zero environmental impact. And as part of our impact analysis, we have found that our current environmental impact is really threefold. Our carbon emissions, that is 1.3 million tonnes in 2019 here, approximately 80% is from our suppliers. Then we also have waste, whereof the most significant part is 500 million prefilled plastic pens that are produced every year and increasing over time. And then finally, also resources summing up everything Novo Nordisk purchases that is, of course, also have a big environmental footprint. So Circular for Zero is addressing all of these dimensions. And our environmental aspirations are really to have circular products, circular company and circular supply. The circular products relates to both new products and how we deal with circular principles in developing those, but it also deals with end-of-life product waste and how we make sure that we do that in a sustainable way. The circular company really looks at how we can have a strong environmental footprint from operations and drive a circular transition across the company, aspiring for circular environmental impact. And of course, we cannot do that without also making sure that our suppliers are supportive of this. And then finally, we will also talk to circular supply that looks to how we can reduce our environmental impact across the value chain. But let's first zoom in on circular products. So please turn to Slide 9. Circularity in designing products is really related to how we make sure that it is integrated in our product development framework. So in our processes, when we develop new products, we have to make sure that new product offerings will be designed for reuse but also for recycling. And we, of course, have a special attention and focus on plastic in this regard to solve the end-of-life challenge as well. The parameters that are guiding us in this is really the carbon footprint, so how many kilograms of carbon per patient per year. We also look at what are the sustainable materials that we can use and also how we can make sure that they are recycled. So these are the focus areas that we have in our product offerings and how we design products for the future. But of course, we also need to look at the products we already have on the market because there's a very long life cycle within pharmaceutical products. And today, we have every year, around 500 million prefilled plastic pens produced and this volume is expected to, of course, increase over time. So what we are looking at here in the end-of-life challenge for products is to see how can we return products allowing for plastic and other components to be reused or recycled. And this year, we are initiating a pilot in Denmark to look at how can we make sure that we, in a good way, take back the pens so that they can be reused and improved use for other purposes. And of course, the purpose of this pilot in Denmark is to make sure that it can be scaled and also make of use in other countries in the future. And to do that, of course, we are not working alone. We have a broad range of stakeholders engaged with us that consist of municipalities, other public bodies, distributors, patient organizations, pharmacies, and also the environmental protection agency. So this is just to say this is nothing we do on our own, but in a strong collaboration with a number of stakeholders. And now I will hand over to Henrik Wulff to give you more details on sustainable production.

Henrik Wulff

executive
#4

Thank you, Camilla. When we are working together on this, seen from a manufacturing and supply chain point of view, then we normally take all 4 quadrants in the strategic aspirations for 25 because basically, we need to serve both the environmental ambitions that we have, but also the financial ambitions that we have. On top of that goes that when we look at new products, and we also look at the pipeline and the segments that we are serving. We try to strike a balance where we can actually optimize our way into the future from a manufacturing and supply chain point of view. That, we have tried to illustrate on the left-hand side on Slide 10 where we have actually drawn our development and sales in our index up against our consumption in manufacturing. And there, you can say that we have been able to basically decouple our sales from our consumptions and our emissions. This work has been -- this year has been further enforced by the environmental impact that we have and the environmental focus that we have. So now we have not only have a financial interest in search from solutions here, but actually also environmental interest. That has become sort of multidimensional efforts in our organization basically to improve our yields and manufacturing, especially in our processes, in our process part but also in our pens that Camilla referred to. Actually, we have been able to develop, together with R&D-standardized platforms where we can actually utilize them across our product portfolio. We are much more focused nowadays to invest in multipurpose manufacturing units that can serve a broadened pipeline and lately, our biggest investment around Rybelsus, both in Denmark and in U.S., has already shown 3x to 4x up capacity compared to what we thought in the beginning. So that means, of course, a lot for our unit cost, but that means certainly also a lot for our environmental footprint when we want to develop that part of the supply chain. Further, another important topic for us is, of course, our partnerships within environmental efforts where we have succeeded in making some long-term engagement with both establishing wind power around in the world and, lately, also solar power, that will also impact it. If you turn to Slide 11. Then if you look further into our CO2 emissions, then we have sort of divided that into our own operations and our own transport and then also looking at our suppliers. That's, of course, a simple way of doing it, but it at least showing our efforts, what we try to do. In the middle of the slide, you can see comparison in the different parts of the 20% CO2 emissions where you can actually see surprisingly high figures from things like company cars and business side compared to manufacturing and product distribution. We are working on all parameters to reduce them. And it's interesting to see how a year like this has developed our understanding in the needs for different elements among company cars and business flights. So we'll work further on that. We have both the local action plans on how we can shift to renewable power in offices and laboratories. We are aggressively following the development within less polluting cars worldwide. We have more times communicated that our usage of business flight will be reevaluated during our experiences during COVID-19 period, and then we will further double down on our use of sustainable energy within manufacturing. If you just look a little further into the supplier part of the equation, then we will basically start working with all our suppliers, but we will start to work, that's on Slide 12. We will start to work with our Tier 1 suppliers that the biggest -- our long-term suppliers where we -- where they are also have ambitions already in this respect. And we have a good already initial collaboration with them and shared understanding on where the world are moving. So it's a good collaboration. Then, of course, we have around 60,000 suppliers. So it's a huge effort going through all the suppliers. But we have started, and it's a good start. Our Tier 1 suppliers, they actually account for 60 out of 300,000 tons of CO2. And so there's a lot of suppliers beyond the Tier 1 suppliers that we need to dig into. To sum up, we will strive for designing our new products for circularity. That means that we will take new materials into use. We will -- we are still very curious to find ways to design a meaningful take-back program. So we can solve the end-of-life challenges that Camilla alluded to. We will continue aiming for Zero CO2 from operations and transportation for 2030. And then finally, the latest one that we have communicated about. Our ambition is to have all direct suppliers to using 100% renewable power when they are supplying us in 2030. Thank you very much, and back to you, Lars.

Lars Jørgensen

executive
#5

Thank you, Camilla, and thank you, Henrik, and we are now ready for the Q&A session on our environmental responsibility. And I would kindly ask you to limit yourself to 2 questions, please. First, let's set of questions.

Operator

operator
#6

[Operator Instructions] Our first question comes from Michael Leuchten from UBS.

Michael Leuchten

analyst
#7

It's Michael Leuchten from UBS. Two questions, please. One, I was wondering if you could speak to capital allocation for projects like your recycling program. Obviously, that requires an amount of funding, but I guess this could easily also be a very steep requirement. So how do you balance the funding versus the time horizon that you're striving for? And that would be question number one. And question number 2, on Slide 10, a very interesting chart where you plot the sales versus the CO2, energy, waste, water. I was just wondering if you could do that in terms of unit costs, rather than looking at revenues when we were to look at this from a volume perspective, how much has the average unit costs come down in terms of the environmental costs that you have on the chart?

Lars Jørgensen

executive
#8

Thank you, Michael. First, Camilla. Can you touch a bit upon the capital allocation for a recycling program, putting -- I know we cannot share the party but some perspectives on that. And then Henrik, on what you can guide in terms of unit cost impact from the CO2 trends. So first Camilla.

Camilla Sylvest

executive
#9

Yes. Thank you, Lars. Thank you, Michael. So on the take-back, it's -- the objective of this is to understand how can we find the best possible way to take the devices back so that they can be recycled. And actually in this process with all of the partners that we have, there is a common interest in making this work out. There is actually, you could say, business opportunities in this for several of the partners in this project. One can imagine, for example, that if people come back to the pharmacy to hand in the pen, then that is also a shop where there might be more business for some of the pharmacies and so on. So the way that the partnership is constructed today is not very capital-intensive at all. Then, of course, this pilot in Denmark is not necessarily exactly the same in all other countries. So now we are learning from Denmark, how this works, then, of course, we will be expanding to bigger scale countries later on, where the setup, in terms of how the system works, might be different. But it's important for us to understand how many of the patients are willing to give back the pens. That's the first and foremost experience that we want to get now and how we do that in the best way.

Lars Jørgensen

executive
#10

Thank you, Camilla. Henrik, what can you share in terms of unit cost and the environmental trends we showed on the slide?

Henrik Wulff

executive
#11

Yes. So there's many perspectives of this regarding which products that we are talking about. But in general, we can say that a 5% to 6% volume growth per year is what we calculate with. And that's a rough number. But even though, based on 5% to 6% in general growth in so-called volumes, then we are able to stabilize our consumptions and our waste. So that's the answer for that.

Lars Jørgensen

executive
#12

Thank you, Henrik. Thank you, Michael. Next set of questions, please.

Operator

operator
#13

Our next question come from Richard Vosser from JPMorgan.

Richard Vosser

analyst
#14

First question, just following up on that reusing of the pen. Is there a thought to sort of redesign the pen so that they could be essentially the out of housing and plastic could be reused, much like the old cartridge pens of the past? Any thoughts again going back there? And just on the program, is there a rebate idea for money for the patient on bringing it back? And then secondly, just on the COVID-impact on CO2, just wondering if you could sort of give us an idea of the quantification of that? And how much of that reduction you see carrying forward?

Lars Jørgensen

executive
#15

So first, Camilla, again, on say sign of the pen for reusability and whether there's incentive for patients to bring back the pen?

Camilla Sylvest

executive
#16

Yes. Thank you. So thanks, Richard. So on the reuse of the pens, it's important for us to, of course, make sure that the pens can actually be reused to something that makes sense when they come back. So at the moment, we have actually tried already with some of our smaller scale pilots, we have tried to reuse the pens for chairs or for other types of materials that make sense as they can use recycled plastics. We are working with another company that can sort of dismantle the pens into different types of plastics that can be used for different types of purposes. And of course, the pen also consists of other things than only plastic. So it's important to be able to split all of this apart in an easy way. And you can imagine that this is some of the things that also, in the future, could go into our design principles so that it becomes easier and easier to do this. We have also actually done some research with patients when we were designing the program as to monetary incentives for bringing back the pens, and maybe it's a little bit of a Danish phenomenon, but this was actually not sort of the biggest purpose for the patients. They, for environmental reasons, would like to make sure that they would support such a program. But this is not to rule out that in other countries, there could be elements of this. But for now, that is actually -- was not part of -- is not part of our program as such.

Lars Jørgensen

executive
#17

Thank you, Camilla. And on CO2 benefit from COVID, you have seen in our reporting so far this year that we have significantly reduced our CO2 emissions, partly because we have now turned into CO2 powering and manufacturing, but also because many of us have been grounded in the locations we are. So we are some 40% down on CO2 emissions. Looking into '21, we believe some of that will continue as we will be, at least as we start the year, restricted from traveling. And overall, we believe we can reduce business travel quite significantly going forward. Thank you, Richard. Next set of questions, please.

Operator

operator
#18

Our next question comes from Mark Purcell from Morgan Stanley.

Mark Purcell

analyst
#19

I'll take 2, please. The first one is on the towards-zero CO2. I just wondered if you could help us understand for a relatively new product like semaglutide, how this has allowed you to redesign your supply chain with respect to suppliers, if you compare that versus older, more legacy products such as [ Sørensen. ] And then secondly, in terms of Rybelsus and oral medicines, I wonder if you could help us understand, if you take your COGs at the moment, what proportion comes from device costs and what comes from API costs? And given the recent deal you did with Emisphere, where your aspirations are now across our portfolio in terms of moving to an oral presentation versus an injectable alternative?

Lars Jørgensen

executive
#20

Thank you, Mark. Henrik, can you say anything about what does it mean when you look ahead at sema supply chain versus some older products compared to the CO2 emissions?

Henrik Wulff

executive
#21

So sema supply chain is, in a simple way, utilizing some of the same facilities and some of the same processes that we use from other APIs. And you can also see our pinch systems around the sema product is similar to what you have seen on insulins and Victoza. So in that respect, of course, the impact of once-weekly compared to once-daily is significant reduction in the consumption, both in our facilities compared -- also compared to what the patients on the supply chain, how they see it. So that's a significant advantage moving from daily to weekly. Yes.

Lars Jørgensen

executive
#22

Thank you, Henrik. And on the notion of now selling all proteins, I cannot go into, say, core split or anything the like on split of devices, API, et cetera. But from a, say, an environmental footprint, it's clear that short-term lower bioavailability and large API volumes will be, say, a negative on CO2. However, obviously, we will save on the plastic component. But we see this as a technology platform that we will be investing in and maturing for the long term. So we think both from a cost and CO2 perspective, there are significant opportunities for us to improve this. So that we can largely take these downward pressure on cost and CO2 down over time. Thank you. Next set of questions please.

Operator

operator
#23

Our next question comes from Carsten Lønborg from SEB.

Carsten Madsen

analyst
#24

It's Carsten from SEB. I was wondering the feedback you have gotten from suppliers since you announced this ambition by being on their behalf that they should also be 100% renewable by 2030. And will you also ultimately then be actually kicking out suppliers if they are not sort of adhering to the targets you are setting for them?

Lars Jørgensen

executive
#25

Thank you, Carsten. Camilla, will you comment on that?

Camilla Sylvest

executive
#26

Yes. So generally, the feedback from suppliers have been very positive. And so we are not in a place where it's needed to make -- to throw anyone out. Actually, we already have a big part of them signing up to do this. And we, of course, also able to share some of our experience. So that's very important for them. And so generally, just very, very positive feedback. And of course, there's also still time to solve this. The earlier, the better, but 2030 is the date.

Carsten Madsen

analyst
#27

If I can just -- can I quickly just pull out one more question?

Lars Jørgensen

executive
#28

Yes, please.

Carsten Madsen

analyst
#29

Yes. Obviously, this is also for Camilla, I guess, or Lars. Do you expect this strict focus on ESG to deliver a comparative advantage for you in the market versus other pharma companies or do you more see that as something that everyone basically will be able to do or will have to do going forward?

Lars Jørgensen

executive
#30

It's a good question. I think in our industry, it is, end of the day, the level of innovation that we bring to the market that determines our success, but it's clear when we deal with governments around the world, the fact that you take a shared responsibility with them in terms of driving health benefits for the population when we recruit employees, when we talk to stakeholders, the fact that we have a strong focus on the environment, makes us a more attractive company to either work for or collaborate with. So I think if you do it well, you can have a stronger standing with your stakeholders who have a significant say in your fortune going forward. So you don't want to fall behind on this, but whether it can really be a sustainable competitive advantage, I would doubt.

Lars Jørgensen

executive
#31

Thank you, Carsten. With that, we will progress the presentation, and I remind you that we have a Q&A session coming up at the end, where you can get back to this particular topic, if you want. So with that, we continue with our social responsibility. And that's back to you, Camilla.

Camilla Sylvest

executive
#32

Yes. Thank you, Lars. And please turn to Slide 15. So earlier this year, at the end of May, we launched our new social responsibility called strategy called the Defeat Diabetes and after thorough stakeholder input and the discussions about expectations for the future and the role of big companies and how they can work to solve societal challenges, we have defined Defeat Diabetes with 3 important elements. And the first one is innovation because the biggest contribution that Novo Nordisk can make is really on innovation given our capabilities. But of course, we also realize that not everyone has access to innovation. So therefore, access to affordable care for vulnerable patients in every country was also important to be -- have as a strong element of the strategy. And then finally, with the progress in terms of new innovations, we can, of course, and access, we can reach a lot of patients but the problem with diabetes and obesity constantly keep getting bigger and bigger because of lifestyle and urbanization. And of course, prevention for that reason also had to be part of our social responsibility strategy. So with those elements, we expect that we can help society rise to one of its biggest challenges. And now I would just zoom in on the 3 elements of the social responsibility strategy. So please turn to Slide 16. And on Slide 16, you see how innovation, as a core element, can help us improve millions of lives. And on the left-hand side, you see today's marketed treatment options and how they can reduce weight loss or how they can achieve weight loss over time. We, of course, expect with some of our new innovations, we will be able to get to an even bigger weight loss opportunity, not only from semaglutide 2.4, but also with our pipeline in question. And with that, we would be able to, within the foreseeable future, get to the level of surgery and what surgery can achieve. So of course, with that innovation, we are able to help improve millions of lives and potentially also save costs for society. We're also working on other transformational treatments for people living with diabetes. We already, at this call, discussed Rybelsus, the first oral GLP-1. But of course, we are also working on a once-weekly insulin, which we are about to initiate Phase III on and a glucose sensitive insulin. And also on digitalization for our connected pens. So with all of this, of course, we are able to bring innovations that can help reduce the long-term complications of people living with obesity and with diabetes and with that, of course, hopefully, also save societal costs. We are also working on, as you know, a stem cell-based program that is likely also to be able to contribute with curative therapies, potentially within Type-1 diabetes as well. So those are some of the core elements of innovation that we are bringing to the market in the future. And if you turn to Slide 17, please, then you will see an overview of the access to affordable care for vulnerable patients in every country that we are also embarking on. Because finding solutions to improve care for vulnerable patients that, for one reason or another in different health care systems do not have access to life-saving medications is, of course, very important for us. So we have committed ourselves to -- in every country where we operate to map who are the vulnerable patients that for different reasons might not have access to care. Sometimes, those groups are minority groups, migrants or displaced populations. They can also be groups of people with low socioeconomic status or limited resources or other underserved populations. We've now completed the analysis in 20-plus affiliates this year, and next year, we expect to complete it for 2/3 of the affiliates or the countries where we work. For each of those affiliates, there will be an action plan in place within a year after the completion. So those vulnerable groups are, in summary, groups that are struggling to get access to essential affordable insulin. There, of course, are also a number of countries where there is already access to insulin where such groups do not exist to a large extent. Then at the same time, we are also looking at -- and we have already this year, reduced our ceiling price for our access to insulin commitment in low and middle income countries. So we have now reduced the ceiling price to USD 3 per vial in 76 countries. And we are, of course, also looking at expanding our Changing Diabetes in Children program with the objective that no Child should die from Type-1 diabetes. Currently, we are operating this program in 14 countries, 10 in Africa and 4 in Asia. And we are expecting to add on more countries next year so that we can reach an ambition by 2030 of reaching 100,000 children compared to the 25,000 children we are reaching today that otherwise would not have access to life-saving medication. And then we are also engaging in partnerships with donations to the World Diabetes Foundation and, of course, also the World Hemophilia Foundation. And we are also supporting humanitarian organizations in times of crisis. And I'd like to emphasize that especially during the COVID-19 crisis, the support needed was, of course, our products, but also our supply chain to bring the products to the right places, where, of course, we have a special capability. So for all of these projects, we are trying to use our core capabilities to a large extent to make sure that we can help and support societies on this. And if you turn to Slide 18, please, you will see an example from the U.S., where 8% of the U.S. populations are uninsured. And of course, these people have -- for them to have developed a number of different access programs that can address some of the issues that they might face if they don't have any commercial coverage or are not covered by Medicare or Medicaid. And we have, as you can see on the right-hand side, a number of programs in place that can make sure that, for whatever reason that a person is not able to get access to insulin, there hopefully will be a solution in place so that they, for an affordable amount, can get access to this life-saving medication. And then if you turn to Slide 19, you will see examples of how we are working with prevention. So the global burden of diabetes keeps increasing. And we also know that to bend that curve on the prevalence we would need to reduce also obesity because that obesity is the leading indicator to get diabetes. The global obesity burden is 650 million people living with obesity and 120 children living with obesity. So a part of our preventional efforts in diabetes is to avoid that more kids will grow up with obesity. And we have recently engaged in a partnership with UNICEF to prevent childhood obesity. And we have started these partnerships in Latin America with the prevalence of childhood obesity in some countries is above 30%. So our midterm goal is to reach more than 500,000 children in Latin America by 2023 and hopefully, some of the learnings from this program can be expanded to other parts of the world. Then at the same time, we're also strengthening our preventional efforts in connection with our Cities Changing Diabetes network, where we, today, have 36 cities enrolled and wherein more than 200 million people are living. And the ways that we do this are very depending on the challenges. For example, in Houston, we have worked with various organizations to target people at risk of diabetes. And in other of these cities in China, we have done educational efforts to make sure that we could support the move of the care to lower-tier segments. So -- and most recently here, in November, we have launched the urban diabetes action framework, which is really an interactive guide to support facilitating cities and countries moving from understanding the diabetes challenge to getting into how do we then implement solutions. So the urban diabetes action framework, which you can also find on our internet at novonordisk.com, really looks at cases, tools and steps to take to get to actionable solutions. And I would recommend that you take a look at that also at novonordisk.com. And now I will hand over to Monique to talk more to how we work with social responsibility also within the company.

Monique Carter

executive
#33

Thank you, Camilla. Novo Nordisk is a company with a purpose-driven culture. The direction is set by the Novo Nordisk way, providing a framework for our culture. It possessed the guiding principles, which underpins every decision we make. And it describes who we are, when we're at our best, how we work and what we want to achieve and sets a clear direction for our company and our employees. Today, we are more than 40,000 employees across the world, with the passion, the skills and the commitment to drive change to defeat diabetes and other serious chronic diseases. Our employees are our strongest assets. And so it's important to maintain our high levels of engagement as you can see here, 92% this year. So we can continue to drive the business forward. Next slide, please. To maintain high engagement, we need to stay competitive. One of the elements is that employees need to have a sustainable workplace. Novo Nordisk aspires to continue to involve the workplace by focusing on 3 areas. The first, we want to organize to win by accelerating diversity inclusion and aspiring for a gender-balanced representation. I'll get back to this on the next slide. The second is to continue to grow our people and be a talent incubator. So we are an organization that consistently grows our talent to fuel the pipeline and ensure that the company has the competencies in place to stay innovative and competitive for the future. And third is to drive cultural change to be an employer fit for the future. To ensure we continue to support the strong culture and foster an environment where our people can thrive, innovate and perform. And I'll get back to how we use facilitation to support the adherence the Novo Nordisk weight and cultural development in a moment. To give you an example of us continuing to evolve our culture, I can tell you about the launch of flexible ways of working, we call this Flex Able. And this consists of 6 ways of working to allow for more flexibility for our employees. So for example, they could conduct their jobs from home, they could work different hours and so on. We have seen that these initiatives that were launched before the global pandemic have actually been accelerated because of the pandemic and are now allowing for more agile ways of working while still fulfilling the business needs. Next slide, please. So diversity and inclusion, our key focuses were Novo Nordisk. And currently, there's a broadly balanced gender representation amongst all managers, which obviously varies between the different areas and the seniority levels where, at senior management levels, it's more skewed towards men. Novo Nordisk aspires towards a balanced gender representation across all managerial levels. And to hold ourselves accountable for ensuring diversity and inclusion is -- has been added to our incentive programs. In addition, local action plans are being made across all areas. Our focus is on ensuring inclusive leadership to enable everyone to be able to deliver their best, everyone is heard, everyone is valued for their unique contributions, and so we unlock the value of diversity and inclusion. Next slide, please. At Novo Nordisk, our purpose-driven culture is defined by the Novo Nordisk Way. And our facilitation process is our way of ensuring this. Facilitations are a proactive assurance done by interviews and assessment of different units in Novo Nordisk by our facilitators. Facilitators are experienced and senior leaders with a strong understanding of our culture and our business role models, you could say. Every year, Novo Nordisk conducts around 30 facilitations with interviews of more than 1,000 employees, 85% of facilitated units are champions of Novo Nordisk Way. When areas are identified for improvement, action plans are outlined to ensure issues are resolved to minimize unpleasant surprises as a way to drive compliance. Facilitation is also used to drive the evolution of the Novo Nordisk culture where coaching elements are used to embed inclusive leadership. We believe this will support our aspiration to ensure we are employee-fit for the future. Next slide, please. So now we've covered social responsibility, both related to Defeat Diabetes, which you heard Camilla talk about and our aspiration of becoming a sustainable workplace. And we would now like to invite for 10 minutes Q&A, which will be moderated by Lars. Over to you, Lars.

Lars Jørgensen

executive
#34

Thank you, Camilla, and thank you, Monique. We're now ready for the first set of questions within social responsibility.

Operator

operator
#35

Our first question comes from Charles Pitman from Redburn.

Charles Pitman

analyst
#36

Charles Pitman from Redburn. I was wondering if you could please just talk to how you aim to keep management employees and suppliers accountable to the society targets? And then on -- for a second question, I was wondering on transparency. Does Novo Nordisk believe the balance between public disclosure and commercial confidentiality in their drug development is currently correct? So for example, does Novo Nordisk think all trial protocol should be published at or before the start of clinical trial in order to enhance their transparency?

Lars Jørgensen

executive
#37

Thank you very much, Charles. Firstly, on best targets. Is that something you will talk to the Camilla? No. Karsten?

Karsten Knudsen

executive
#38

So the accountability on -- Charles, could you repeat the question? Your first part of the question around accountability and anchoring repeat that please?

Charles Pitman

analyst
#39

Sure. So you've talked about the systems you've got in place to monitor and survey how employees are following your targets and keep in line with the kind of pure societal workplace. But I was wondering how you keep management and also then suppliers accountable to achieving improved societal targets?

Karsten Knudsen

executive
#40

Yes. So thank you for that question, Charles. I will come back to in our governance section around how we do assurance and different assurance measures we're taking. So if I could ask you to park that question until then, then I'll get back to it and happy to elaborate on that one.

Charles Pitman

analyst
#41

Sure. And then just on transparency?

Henrik Wulff

executive
#42

Sorry, so the transparency. [Technical Difficulty]

Lars Jørgensen

executive
#43

Next set of questions, please, if there are any.

Operator

operator
#44

Our next question comes from Martin Parkhøi from Danske Bank.

Martin Parkhoi

analyst
#45

I have 2 questions. Firstly, one, on the follow-on brand, why have you only launched a follow-on brand in the fast-acting segment, why have you not launched a follow-on brand in the basal insulin segment in U.S.? And then the second question for maybe a little positive question. You explained in the earlier presentation that you have been able to improve the production capacity for Rybelsus by the 3 to 4x versus initial expectations. And you celebrate that by getting a better gross margin, why we're not celebrated by offering a lower price to the patient?

Lars Jørgensen

executive
#46

Thank you, Martin, for those questions. On the follow-on brands, I would say that this was one of the initiatives we took in the beginning of the year to try to alleviate some of the affordability issues in the U.S. So it is one of, I think, three initiatives. And we upfront didn't know how it would be received. It has been well received. And I think that leads to us, obviously, considering what more to do in that arena. So I cannot be more specific on it now. But obviously, it's encouraging to see that it's actually helping patients. In terms of production capacity and improving yields, et cetera, I think you know that we come from a lower profitability initially than for other products. So I think in the all area we are working on getting up to the margin we have on other products. And we are pleased with the trends, obviously, and then you can say what we do in the market is a function of the competitiveness of the market. So we price based on the clinical value that the product brings compared to other products, while at the same time, looking at the most vulnerable patients, as Camilla spoke to those who, say, fall outside of the normal market conditions, and we take a special responsibility for those. So it's a market we compete in. And then we have an eye for those who fall out of that market, and that's how we, I believe, we can say that we take our social responsibility while still being a business. So balancing 2 of the Triple Bottom Line dimensions, social responsibility and financial responsibility. Thank you, Martin. And next set of questions.

Operator

operator
#47

Our next question comes from Michael Novod from Nordea Markets.

Michael Novod

analyst
#48

It's Michael Novod from Nordea Markets. Just one question that relates to obesity and the skewness that's often in terms of social status and wealth, et cetera, which is also education. And the product that you're launching in general for obesity are higher priced products. So how do you address social responsibility with the obesity portfolio, and also in terms of how do you then place potentially Saxenda versus semaglutide in that business environment in order to focus more on social responsibility in obesity?

Lars Jørgensen

executive
#49

Thank you, Michael. Camilla some perspective on that?

Camilla Sylvest

executive
#50

Yes. Thank you, Michael. So of course, we are carefully looking into what are the barriers for obesity treatment. And at this point in time, it's not the price that is the main area. It's really the number of people who will seek advice from their physician. And when they then go to see the physician, we also know that it's a fragment of the physicians that then decides to treat with pharmacy therapy, a lot of them decides to treat with the exercise and diet, which, of course, also for some people will work. But we, of course, are working on solving some of those parameters and I can say even within diabetes, we still have the Rule of Halves problem. That means that only half of the people are diagnosed, and of those diagnoses, only half are being treated. And again, those -- only half of those are getting access to a treatment that brings them in good control. So in obesity, this is even worse. So we are trying to improve on some of these infrastructure issues, along with, of course, launching better and more efficacious products so now we will submit, as you know, by the turn of the year as the semaglutide 2.4 for submission in the U.S. and EU and with that, we are bringing quite an innovative product to the market, of course, that we hope can help support many more people in achieving a significant weight loss. So that is our focus as we spoke to before, innovation is the core element of our social responsibility strategy. That's how we made the biggest difference. And then, of course, we will follow-up and making sure we also look at access later after the launch of that.

Lars Jørgensen

executive
#51

And talking about access, you saw that we have developed an agreement with the U.K. regulator nice. And so of course, we have to work hard on making sure that we can talk to the value of actually treating people living with obesity and the more established health care systems acknowledge that. And we build reimbursement, we also secure broad access and, say, a social profile for also those who cannot afford out of pocket. So it's a new area. And a new area will always be determined by, say, level of innovation. And typically, you have the high end of the market getting access first. Thank you, Michael. Next set of questions, please?

Operator

operator
#52

Our next question comes from Trung Huynh from Crédit Suisse.

Trung Huynh

analyst
#53

Just 2 questions from me. First one on transparency. So that in regards to pricing and access. So you focus on pricing approaches to help with the poor in the U.S. where you've expanded your affordability offerings. And in the ex U.S., you've focused on differential pricing policies. But one thing we get less details on is the transparency of pricing. So I'm curious to know how you aim to be more transparent to shareholders, stakeholders worldwide about how you implement these pricing approaches? And then secondly, very quickly, just in terms of the affordable patient access, how does that go beyond insulins? Do you have any programs you're looking at with the GLP-1s?

Lars Jørgensen

executive
#54

If I take the general question first and then maybe, Camilla, you can talk to the affordability program, including GLP-1. So our list prices are transparent, they are known. Obviously, in the U.S., we don't disclose per product rebates, but we do disclose what our aggregate rebate levels are. So you can see how that develops year-over-year in the annual accounts. So we have, say, the blended net price, so to say, in the rest of the world, our pricing is also largely available and known. In a few countries, you have rebates agreed with the payers but largely, those prices are known. The affordability programs are also very well disclosed how you qualify for free insulin pension in the U.S. The differential pricing policy with a $3 a vial program, et cetera. So I believe we try to be as transparent as possible, but we are not in a position where we can disclose rebates per product because they are confidential in the contracts we have with our customers. Camilla, on the affordability programs broadly in the U.S.

Camilla Sylvest

executive
#55

Yes. So more broadly, on the affordability programs, we have initiated our affordability programs, mainly on insulin, both in the U.S. but also worldwide. Because insulin is a life-saving product. So it has been important for us that we establish those with insulin initially and then, of course, potentially down the road, we could look at other programs. But our key concern has been that people should not die from not getting access to insulin. So we're trying our best to make sure we can support the most vulnerable patients in every country.

Lars Jørgensen

executive
#56

Sorry, I will close this section with this. And I understand that my microphone was muted when I answered the question on clinical trials, transparency. I apologize for that. What I said was that we always communicate when we start clinical trials, what the endpoints are, and we always publish our data. If there's need for more detailed insights to what we do, please get back to our Investor Relations officers after this call.

Lars Jørgensen

executive
#57

Thank you. So with that, we'll go to the last section of today's agenda, which is corporate governance, and over to you Karsten.

Karsten Knudsen

executive
#58

Great. Thank you, Lars. This section will cover both the corporate governance, but also how we govern sustainability governance and how we anchored in our remuneration. And finally, how we report on our performance on sustainability on an ongoing manner. So please turn to the next slide. In regards to our corporate governance setup, then, of course, the starting point for Novo Nordisk is that we conduct our business following all Danish and international laws and regulations. In addition to that, we base our business on the Danish corporate governance recommendations as designated by NASDAQ Copenhagen. In the company, our government structure is a so-called 2 tier structure with the Board of Directors consisting of 9 shareholder elected members and 4 employee elected members, thereby ensuring that the employees are heard in the boardroom. Separate from that, we have an executive management consisting of 9 members. The management structure is then complemented by a set of assurance measures as we got the question from Charles before. So the assurance we're conducting to ensure that we are following all the relevant rules and regulations is manyfold. So first of all, in terms of our financial data, then, of course, we have external audits as are statutorily required for all companies. On top of that, we have an internal audit function. And as goes our social and environmental data, as you can see in our annual report, they are also reviewed by our external auditor. Then as Monique covered, then the our internal behavior and how we behave in the company and adhere to the Novo Nordisk Way is being reviewed by our facilitators that are providing facilitation reports on our behavior. And then on top of that, then, of course, we also have quality audits and inspections, both internally and externally, and that goes both for our clinical trial conduct as well as for our supply chain, thereby ensuring that we're following all the relevant -- all the laws and regulations in this area. Please turn to the next slide. When it comes to sustainability governance, then there's a broad range of international standards and principles, and I pulled out a number here, which forms the base for how we anchor our internal behavior in regards of sustainability. So the way we have structured our sustainability governance is that we are -- we start out with the international standards and principles for responsible business conduct that would be the UN Guiding Principles for Business and Human Rights, OSD guidelines from multinational enterprises, UN Global Compact as well as a number of other standards, including TCFD, SASB and as you see in our annual report and as Lars mentioned in his opening, then we are, for a number of years, reporting based on integrated reporting setup. Furthermore, we, of course, follow the compliance requirements, for instance, as defined by the U.S. FCPA and the U.K. Bribery Act. So that creates kind of the society's expectations and regulations as to what a sustainable enterprise is. Then Monique covered the Novo Nordisk Way. So the principles, how we work. And part of that is also our Triple Bottom Line principles where we balance social, environmental and financial responsibilities. Then double-clicking on those principles. We have defined a global set of standards and codes of conduct, and thereby, basically taking those more overarching principles and making them relevant for our employees on a daily basis. So we have created a set of guidelines covering environmental responsibility and responsible workplace, bioethics, responsible sourcing, a business ethics code of conduct, I'll get back to and a sustainable tax approach will also be coming back to. So thereby, what you see in our external reporting. Of course, the triggers to make our sustainability approach integrated in how we conduct business on a daily basis by all 40,000-plus employees of the corporation. Please turn to the next slide, Slide 28. So one concrete example is how we anchor business ethics in our business on a global setting. So the starting point is that we operate on a global scale in many markets and in many different markets. So how do we anchor a business ethics mindset, both on a global scale and across the value chain of the company? It all starts with a Novo Nordisk Way, as you saw before. And one of the key principles in Novo Nordisk Way is as the quote says, we never compromise on quality and business ethics. So that's the foundation for our business ethics approach for the company. Then the way we've done it is that we start out by identifying what are the key trends in the societies in which we operate, and what are the key risks in that context. And some of the key risks could be whether our sales representatives are adhering to the codes around product promotion, and what are the practices around corruption and the rules and regulations there and how third-party representatives are representing the company. So the way we then implement that in how we operate as a company is that we have created a business ethics code of conduct. And that basically states how we operate in the company around the globe and what we expect from our employees and also how third-party representatives should be operating. Then that is implemented through training for all employees in the company management. And we have annual training in the company and in the form of e-learning. And based on that, we verify on an ongoing basis, how we're performing on a business ethics point of view. And we do that both in terms of the audits and insurance activities I was discussing before, so that could be group internal audit doing reviews in the different areas of the company and geographies. It's also a function of the compliance hotline where we -- where employees and external parties have the opportunity to report any issues to an independent hotline, who would then review and take proper action for the reported cases. Then based on these activities, we have reporting, both in our annual report in terms of employees trained in business ethics in a number of business ethics reviews. Furthermore, we have reporting internally in the company, both to management and the audit committee and the Board in terms of findings both in terms of our internal audits as well as trends and observations from the hotline and relative -- and relevant actions taking as a consequence of that. Please turn to the next slide. Another core area of running sustainable business is to have a sustainable tax approach. And as disclosed on the Novo Nordisk website during the past few months, we have defined a sustainable tax approach, which has been approved by the Board of Directors earlier this year. Our sustainable tax approach is 3 pronged. So first of all, our tax approach is commercially driven, and commercially driven means that our business structures, our legal structures, they are driven by commercial considerations and not driven by tax considerations. So we set up our structures based on where we do business. As a consequence, we do pay taxes or we pay taxes where value is generated by the underlying business that we're in. And when you look at our tax rate, that is, of course, another part of being commercially driven tax approach, and our effective tax rates, which we are guiding currently, is in the magnitude of 20% to 22% very closely resembling the geographies in which we are operating on an average basis. The third -- the second part of our sustainable tax approach is responsibility. So we are not setting up artificial tax structures or tax savings. So again, we have set up our structures based on our business structures and where we do business and where we generate value for shareholders and for society. Another part of being a responsible -- having a sustainable tax approach is also that we have set up transfer pricing principles, which are compliant with the OECD guidelines, and part of that is that to ensure predictability around our tax rate, and also ensuring that the tax authorities around the globe are understanding our setup. We have entered into so-called advanced pricing agreements covering to the [ tune of ] of 65% of revenues. And advanced pricing agreements for those of you who are not kind of detailed into taxation is basically mutual agreements between tax authorities in different geographies who are agreeing on taxation of Novo Nordisk profits between those geographies. On top of that, then the third element of our sustainable tax approach is transparency. And the transparency part is both layered into our tax approach, which are posted on our website. It's also driven by the fact that given -- since we have 65% coverage with our advanced price agreements -- pricing agreements, then tax authorities do have insight into how our profits are taxed across geographies. Furthermore, then we are, of course, adhering to the EU directive around tax reporting on a more detailed basis to tax authorities. And then finally, we have started reporting our total tax contribution. So even though our corporate income tax is closer to the DKK 10 billion mark, then as you see -- then as a company, our total tax contribution is closer to the DKK 28 billion mark when you include indirect taxes and withholding taxes. Please turn to Slide 30. Then anchoring our sustainability approach in terms of putting the hand on the store, you can say then then we have anchored our sustainability approach in remuneration. And just covering our remuneration approach for the company, it starts with our remuneration policy, which you can find on our website. It was recently AGM adopted earlier this year. Our remuneration policy is designed to attract and retain executives and Board of directors, and it's based on a benchmark of Nordic general industry and EU pharma corporations. Then we combine the remuneration policy with our strategic aspirations, which are basically the ambitions for the company in years to come based on our corporate strategy. And based on that, both short and long-term remuneration are paid out based on targets from our strategic aspirations, and the remuneration payout is then reported in our remuneration report. We issued our first remuneration report earlier this year, and you'll see our 2020 remuneration report in the first quarter of next year. Please turn to the next slide. Then as other parts of running our business and conducting our business, we have, on an ongoing basis, been reporting on our financial results, on our market shares, on our progress on our pipeline and doing performance management on sustainability is in relative, fairly similar in the sense that we set out -- we prepare a strategy, we set out an ambition, and then we will keep score. And the way we keep score you will find predominantly in our website, but also in our ongoing reporting. So what you'll be finding in our 2020 annual report, which, again, is based on the integrated principle of both covering financials, but also sustainability metrics. But you'll be finding a number of metrics on our sustainability performance, both in terms of environmental performance that could be, for instance, CO2 or waste or resources used. Our social statement in terms of both donations or children's treats according to our Defeat Diabetes strategy and finally, our approach to governance and including a number of other metrics, where we are basically combining or reporting on our performance on our overall sustainability approach. Please turn to the next slide. So as you saw in the previous section, then we have clearly defined governance structure, compliance and assurance approach associated with that. Our sustainability approach is defined, and it's integrated in how we run our business. So it's not a separate standalone, it's an integrated part of how we run our business. And it's also integrated in how we report on our business. And actually, it has been so since 2004. So with that, back to you, Lars.

Lars Jørgensen

executive
#59

Thank you, Karsten. So we have now reached our closing Q&A where you can ask questions to the corporate governance topic discussed by Karsten or you can follow-up questions to one of the first 2 topics, environmental responsibility or social responsibility. So first set of questions, please.

Operator

operator
#60

[Operator Instructions] Our first question comes from Peter Sehested from Handelsbanken.

Peter Sehested

analyst
#61

It's Peter Sehested. I have just two. With respect to prevention, last time I checked, Novo Nordisk was a pharmaceutical company and the STEP program is clearly a display that you have some kind of core competence in developing drugs for the treatment of obesity. But I really can't understand how you have competencies in preventing obesity and whether you should not leave that to, let's say, people who are more adept at that and, for instance, spend the resources on that on something perhaps more valuable, for instance, investing more in developing treatments that can actually cure diabetes. So that and whether -- and that relates to my second question, which is why you are not more ambitious with respect to stating clear goals for time line, et cetera, and how to have a treatment for or cure for diabetes on the market, that would, let's say, fit well with your ambition being a leading diabetes company but also would fit well with your social responsibilities?

Lars Jørgensen

executive
#62

Thank you, Peter. So I hope I heard you right, your sound was very low. But your question to why we engage in prevention and don't let that go to others, I will refer that to Camilla, and then I'll try to answer the second question on time line for curing diabetes.

Camilla Sylvest

executive
#63

Yes. So we are very much engaged in preventing also obesity, but always with partners. So as we just talked about, we have teamed up with UNICEF, and we will also be looking at other stakeholder coalitions. We have also teamed up with behavioral change companies in other parts of the world where we're looking at how can we combine behavioral change with pharmaceutical products potentially later on to treat, but also earlier on to prevent obesity. So it's important for us to understand the link between obesity, diabetes and also cardiovascular disease. And as many of these 3 diseases can be prevented the same way, there is an opportunity for us to engage in this with partners, of course. So right now, we are in a stage where with childhood obesity, we hope that we can achieve some learnings, which we can then later on also export to other parts of the world.

Lars Jørgensen

executive
#64

Thank you, Camilla. And in terms of why not being more bold and set a deadline or time line for curing diabetes, had we done that years back, we would have failed miserably. Having said that, we have a number of exciting programs. If you look into our stem cell-based research, that is so far a 20-plus year commitment, which, from the get-go, was focused on finding a cure for Type-1 diabetes. We have now established the platform and can -- we have demonstrated that we can produce the cells in a GMP-compliant way. We are also figuring out how we can mature the stem cells into different type of cells. And now we're approaching first clinical trials. First will not -- first one will not be in diabetes. But after that, we believe there is an opportunity to also test out our stem cell approach within Type-1 diabetes within a few years, if all goes well. So that's, you could say, prevention of Type-1 diabetes from the get-go, not for all patients, but for those who are struggling the most in controlling their glucose level despite the modern medicines we know of today. You can say, dealing with obesity, either preventing obesity or treating obesity, is also indirectly prevention of Type-2 diabetes. And you can say that's maybe an indirect way of treating a disease, but we believe with reference to what Camilla said, that we can play a key role not only treating a chronic disease, but also preventing it and collaborating with the stakeholders. So within a few years, we might be making the first kind of steps on the moon in terms of starting the journey to cure Type-1 diabetes. Thank you, Peter. Next, set of questions, please.

Operator

operator
#65

Our next question comes from Wimal Kapadia from Bernstein.

Wimal Kapadia

analyst
#66

Wimal Kapadia from Bernstein. So can I just ask a little bit more on the new remuneration policy. When I compare versus your peers, number management actually seem to be very good value. But can I just ask about what the ESG factors are included within your remuneration policy, and how much weighting do they actually have? Just trying to get a sense of the ESG drivers and compensation and how accountable management is with respect to this from a compensation perspective. And then you briefly touched on -- my second question is, you briefly touched on this, but can I ask furthermore insight into safety and clinical trials, data disclosure of these trials; and finally, product quality and safety. Now some of your competition have been hit negatively in recent years. So maybe you could provide a bit more color on how Novo ensures these factors are considered? You mentioned facilitation as one method, but can you talk more about the specifics for these factors?

Lars Jørgensen

executive
#67

Thank you, Wimal. First, Karsten, on remuneration and how these factors are incorporated.

Karsten Knudsen

executive
#68

Yes. So -- sorry Wimal. I just had to unmute myself. So I was saying that, clearly, some of the ESG factors are more difficult to measure than financial metrics like profits or commercial metrics like market share. So the metrics we include are basically some of the metrics that Henrik, Camilla and Lars were talking to and Monique were talking to before. So metrics could be something around progress on the social ambition on our Defeat Diabetes strategy. It's also on our environmental agenda, it could be CO2 emissions. And as Monique talked to also, then actually on our remuneration, diversity is a metric this year also on which remuneration is based. Then as to the weight. And again, I would refer you to both our remuneration policy and the remuneration report on our website for more granularity. But what we do base it on is that we have the 4 quadrants in our strategic aspirations, and all 4 quadrants are tying into the remuneration both on the short-term incentives as well as the long term incentives. The main difference between short-term and long-term is that there's also an individual element in the short-term incentive program, whereas the long-term incentive program is -- does not have an individual element. But you can see both duration and overarching principles. So in the long term, you should expect that to include both financial metrics, commercial metrics and then progress on pipeline yielding long-term value as well as progress on our sustainability ambitions that we just talked to.

Lars Jørgensen

executive
#69

Thank you, Karsten. And on, say, the quality of our clinical work Wimal, it's not an exact science, and it's not an easy question to answer. But you can say, we spoke about our Novo Nordisk Way just before, and we have these 10 essentials, which all employees are trained in and guided by. And the first one is to be patient centered. And there's another one on as you heard before, that we never compromise on quality and business ethics. So we have a very stringent view in how we look at data. And if we see signals, if we have quality issues either in [ conduct ] or in manufacturing, we react on it. In management, we have twice a year a quality management review where we review quality performance, not only of clinical development, but also in manufacturing. And I can promise you that we take this very seriously. In our annual accounts, we report on a number of product recalls, et cetera. And executive management are -- is involved in each and every assessment of a potential product recall if there's anything of a signal from use of our products or anything that goes wrong in manufacturing and the same goes for clinical trial conduct. If you have more, say, detailed questions or need for discussion, this more in detail, please get back to our Investor Relations officers. Thank you, Wimal. Last set of questions, please.

Operator

operator
#70

Our next question comes from Trung Huynh from Crédit Suisse.

Trung Huynh

analyst
#71

Just 2. So first one, one of the biggest areas and problems of pharma has been off-label prescribing and that -- the inappropriate influence with doctors. So there's some concerns over the links with sales force remuneration based on prescription levels. So can you just tell us a bit more how Novo does things differently, perhaps especially in the international markets where the reps can perform quite an educational role? How do the reps incentives for Novo salespeople compare with your peers? And then finally, just a more holistic question on the rating indices. So there's quite a wide range of ratings for individual companies looking at different indices, making quite tough for us to rely on a single one. So my question is, is there anything you think these indices do particularly well? Is there anything they do poorly, just given issues that are not -- they're not always black and white? So which indices do you think are the most thoughtful in grappling with these issues?

Lars Jørgensen

executive
#72

Thank you, Trung. Camilla, first, on some perspectives on how our sales force is incentivized, what kind of messaging they do potential links to off-label usage. And then Karsten, you can get into -- if any views on the different rating indexes and our perspective on that. Camilla?

Camilla Sylvest

executive
#73

Yes. Thank you. So it is though that in all of our countries, we have a business ethic framework in place where we train all of our reps to make sure that the way we promote our products are completely consistent, of course, with the local regulation but also with the Novo Nordisk regulation. So it means that if the Novo Nordisk regulation internally is stricter than the local regulation, then we will always follow the most strict regulation. We do audits of this also with our facilitators that Karsten talked to before. We also have, of course, trading programs, and then we do sample checks. So especially in emerging markets like China, we have relatively deep sample checks of everything that takes place, and we also have digital solutions to try and track variations to such things. When it comes to how the remuneration of the web is compared to industry, I think we are relatively aligned with the majority of the industry in general.

Lars Jørgensen

executive
#74

Thank you, Camilla. Karsten on the different ratings and our perspective on that?

Karsten Knudsen

executive
#75

Yes. Yes. So in terms of sustainability ratings and ESG in general, then as with the different standards that are available, then this is an emerging area. And what we have learned over time is that that the key triggers for us to do something, which makes a difference and is meaningful in the context of how we run our business and what our strategy is. And as we do so, then making that transparent in our reporting and ensuring to drive progress. And based on that, and you saw initially in Lars' presentation, you saw the sustainability ratings, which are very competitive compared to many, many peers. It's important to note, we have very, very strong ratings, but we're not doing this for the sake of the ratings. We're doing this because we want to drive a responsible business, and it's part of our overarching purposes as a company. And then as a consequence of driving this agenda for a long time and being transparent around it, then we get a very good performance by a number of the agencies.

Lars Jørgensen

executive
#76

Thank you, Karsten. Thank you, Camilla, and thank you. So with that, we close today's call. Thank you for your interest in Novo Nordisk and our approach to running a sustainable business. You can find more information on our website, and I encourage you to contact our Investor Relations officers if you have need for more information. Thank you all for today. Bye-bye.

Operator

operator
#77

Thank you. This now concludes our conference call. Thank you for attending. You may now disconnect your lines.

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