Penumbra, Inc. (PEN) Earnings Call Transcript & Summary
August 11, 2021
Earnings Call Speaker Segments
William Plovanic
analystGood morning. Welcome to the Canaccord Genuity Annual Growth Conference 2021. My name is Bill Plovanic. I'm one of the senior medical device analysts here at Canaccord. With us up next, we have Penumbra, and we have the President, CEO and Chairman, Adam Elsesser. The format for today is going to be a fireside chat, and I'll remind everybody that we do have a web link that you can ask questions. You can also e-mail them to me as well at wplovanic@cgf.com. With that, I'm going to kick this off today. Adam, thank you for joining us.
Adam Elsesser
executiveMy pleasure. Thanks for having us.
William Plovanic
analystAnd then just for -- I'd be surprised if people didn't know who Penumbra is, but actually, I have gotten some inquiries over the past week. So -- not very familiar with the company. Just give a brief high-level overview of the business for those folks that might not -- that are new to the story.
Adam Elsesser
executiveYes. Well, thanks. Real brief -- we're a health care company focused on medical devices. We started some years ago in 2004 with this crazy idea that we could create a product that would go into the vasculature and up into the brain and get clot out when you've had a stroke and see if the patients will recover and do better. That developed pretty well. We knew we had to keep iterating and iterating and innovating, which became sort of the most important part of how we saw our mission. We've moved those same skills at innovation into other areas, vasculature, the peripheral vasculature and now VR. And we're set up to continue to help a huge number of patients who are suffering from a variety of medical conditions. So I think we're known for that ability, that innovation, that sort of constant ability to keep getting things better and better, and it's put us in a pretty good position.
William Plovanic
analystThank you for that. Listen, I know on the last analyst call -- investor call, we talked about the upcoming Investor Day next month that will give us details on the real VR business. So just for all the folks out there listening today, this isn't going to be a real VR question-and-answer session. I'm going to -- I don't want to steal the company's thunder for next week, and I doubt Adam would answer your question on it. So we'll kick it off with the peripheral vascular business, which is now your biggest and fastest-growing segment. Talk about the overall market opportunity that you're targeting with this and then even some of the market dynamics.
Adam Elsesser
executiveYes. That's a great question. We have a couple of different parts of that business. Our embolization business, which has done really well. But the real core that -- the part of the business that I think has the largest long-term opportunity is the thrombectomy part of the business, where we're removing clot from the arterial side, the venous side, PE cases and so on. And that really for us is just so exciting to watch the change, even in the past year or so in the attitudes of customers and sort of the way they're thinking about it. A little over a year ago, we launched our first Lightning platform, Lightning 12, which really, I think, has sort of reset people's thinking. Here, the challenges have been, how do you remove so much blood clot in this -- in large spaces like in PE in veins without taking too much blood and doing all that. And Lightning really changed the game in there, where you don't really have blood loss with Lightning, you're only removing clot, it's minimal. So you don't have to deal with blood loss. You don't have to put it back in or do any of that other stuff. You simply do the case the way it's supposed to be done. And that franchise now expanded with Lightning 7 into the arterial side. And I think it's laid the foundation for what we think is going to be some really, really good work over the years ahead. The biggest competitor we have is the use of lytic to drip tPA over a couple of day period, usually with the patient in the ICU or a monitored bed. And a year ago, nobody talked about what we were doing as anything but sort of mechanical thrombectomy. Now everyone is referring to it as single-session therapy as opposed to multiple-day therapy. And that might be a simple bit of terminology, but it really is a signal that the work that's being done is -- it's working. People are starting to be open to doing something different than they've done for so many years. And it gives us a huge amount of optimism going forward. That and of course, the fact that the technology itself is performing so well and hospital systems are sort of recognizing that. I think we're in pretty good shape. It's going to take time. It's not going to be one of these just crazy, crazy things that all grows at once because you're really going one by one, doctor by doctor, to have these conversations. But as this past quarter and going forward into this back half of the year, our guidance shows, we have a lot of confidence with the technology and how it's standing up and people's reaction to it. So we're in pretty good shape. And I think we can help an awful lot of people with this.
William Plovanic
analystIt seems like the body of that clinical evidence, the awareness, the COVID has really had a significant driver for a lot of that, right? Just due to the dynamics and the needs in the hospital. I don't know. And your thoughts, mine kind of it seems like it probably accelerated the development and transition of this market from lytics to single session much faster than we've seen in other areas.
Adam Elsesser
executiveYes. I think there -- I don't want to at all overstate that. Last summer, that was definitely what people were -- the fact that ICUs filled up and therefore, made it a challenge to take an ICU bed to drip tPA for a few days. That was just a practical dilemma. I don't -- barring the exception of 1 or 2 small situations in the field right now, that's not really what's going on. COVID isn't driving those decisions. And some of the early other issues right at the beginning, there were a lot of these anticoagulation issues, and we saw clot in COVID patients. It still happens, but that -- for many, many months, that's not what I think is driving this at all. And I think it really is back to sort of the more basic work of the patients that do have clot, and there are hundreds of thousands of them independent of COVID. Let's move the market to doing single session sort of easier therapy, better for the patient, better for the cost structure of the hospital. So I think COVID may have been a bit of a -- like a spark back last year. I would say all of this year and going forward, it's not likely playing a significant role, at least from what we hear in the field.
William Plovanic
analystAnd then another question from the audience is just in terms of the dynamics you're seeing in that business relative to COVID, do you think it's lifted and then kind of the wave -- with the waves you get these lifts in ebbs and flows? Or how would you characterize what that has done? You mentioned last summer it was the spark, I agree. That's probably the best way to -- better way than I articulated it. But how would you see that as it's flowed through kind of Q4, Q1, Q2 as you think about the business?
Adam Elsesser
executiveYes. I don't -- I don't think it's negatively or potentially even positively impacted the business this year at all in terms of the thrombectomy side. On the embolization side, we called out on our earnings call a small portion of our embolization business was likely sort of catch-up cases that hadn't been done, needed to be done urgent, if you will, but not emergent, and that might ease, but that's a relatively minor piece of the business. On the thrombectomy side, I don't think, as we see it, COVID is going to play a particular impact. Obviously, if things get worse and worse, that it's likely not going to happen, but then we don't know. We can't predict what happens in that case. But right now, we don't see that playing either a negative or a positive impact.
William Plovanic
analystAnd I think -- I love having these conversations with you because, I mean, you have such a unique perspective given you've watched this happen in the neuro market and you're watching it happen in the peripheral market. But is -- and you've had to compete there with some really big players. What's the 1 or 2 biggest differentiators for you versus the other players in the market, would you say?
Adam Elsesser
executiveOn the peripheral side, it really comes -- I think it just comes down to the technology. And you got to remember what are you trying to do? What are you -- what is the device trying to do? The device is trying to remove all the blood clot as fast as possible and safely without doing any ancillary damage to the valves or anything else. And so the products are designed for that. Before we had Lightning, we had a smaller system because we didn't want to have any safety risk around taking out too much flood. And that was a limiting factor. It worked, but you had to be patient. It took a little longer, and we needed to improve that. And we did with Lightning 12. But the most important thing is even though our current portfolio was working really well, and as I said, we're seeing a significant increase in usage in cases, we're not done innovating, just like we've never been done innovating on the neuro side. And we're pretty excited because we think we can continue to improve this technology to the point where you're just getting the clot out faster and faster and easier and easier in a safer and safer way. And in fact, sort of democratizing the procedure to any of the operators. And that's pretty exciting to feel. And I think between where we are now and where we're going to be in a year or 2, we think we're going to help an awful lot of people.
William Plovanic
analystExcellent. I think 1 or 2 more questions on peripheral and then we'll switch over. But how different are their need? I think as more companies compete in these different subsegments of this whole peripheral thrombectomy market, it's parfay that we keep going through the layers and learning more about. But how different is venous, the needs for venous, arterial and coronary as you look at those different kind of subsegments?
Adam Elsesser
executiveWell -- so we'll start with coronary. Coronary Is a very, very different thing. And the needs there are very particular. The clot tends to be much softer and easier. And it's really an ancillary to a larger -- not always, sometimes the clot is the main issue. But most of the time, it's ancillary to other things that you need to do. So that's sort of a very unique thing that we can sort of put on one side. The venous side, between DVT, PE and arterial, the product -- the concepts can be the same. We're moving the clot mostly using aspiration. But how the tool works, the size of the tool, the blood loss issues, all that. Those are all going to be a little bit different. And again, you have to deal with the valves and DVT and make sure you're not damaging those. So there is technological differences. And obviously, even on the arterial side, your -- it is a different product, it's going below the knee versus above the knee, depending on the size of the artery. So by definition, the products at some point start to -- and you see that with our sizing on Lightning, and there'll be some continued differentiation. It's not one size fits all. But the core philosophy is the same, which is to sort of do it as quickly and safely as possible. Again, all the other companies that are in this, I think, at this stage, unlike neuro where the field was already sort of developed, everyone had done the work, the trials, where this big moment back in 2014 and '15 that sort of defined the sort of starting point of the growth. Here, I think it's going to be a longer road as we continue to move into that direction. And having a lot of other companies talking about it and encouraging people to go to sort of single-session mechanical thrombectomy as opposed to lytic or, in certain cases, an artery surgery, I think is a really valuable moment. I'm not in the slightest bit anxious about that. I might be if I didn't think our technology would rollout. But I'm not at all anxious about that. I think more voices, more discussion is going to be necessary to sort of move a field. And again, I want to remind everyone, people have been doing lytic drip for 20 years and with no data. There's no data that says that's good, and they're doing it because they have to. These patients have to have something done to them. So they do that. So to switch them is going to take time. And I think it's great. I think in the long run, and we don't try to go head-to-head. There's no need to go head-to-head. There's so much greenfield here. But in the cases that we have, and there's a hospital system recently that had to pick between the 2, they picked us. I think we're going to be in pretty good shape. But most of our efforts are focused on the greenfield in this opportunity, and it's pretty good right now.
William Plovanic
analystLast question, just we're seeing this -- your partnership with RapidAI, that helps the PERT teams [indiscernible] how important is this to development of the market? How necessary is it today? Or is this kind of for something that you'll need to kind of keep that penetration up in the out years?
Adam Elsesser
executiveYes. I think the work that Rapid is doing, and I'm really proud of them. They've done such great work in stroke around imaging and quantifying that. And as important, the workflow and communication tools that their mobile application has done with the physicians. It's a multidisciplined specialty in PE -- that you've got a bunch of different people sort of weighing in on the treatment paradigms of those patients, just like in stroke. And to connect everyone, to be all on the same page, be able to communicate. And eventually, we'll have enough -- they'll have enough information to really start to use that in a more substantive way. I think it's critical because right now, it's very informal. There's all these PERT teams that are trying to formalize it. But if you have a software that connects them all and enables that even faster, there's no question you're going to get better treatment and better decision-making for those patients. So I'm really proud to be part of helping them, encourage them, getting it out there. Their installed base in the neuro world is so dominant that most of the hospitals already have it. And so this becomes more of an add-on. I'm tickled. I think it's going to be an important development for the field. And just better decision-making for the patients.
William Plovanic
analystClarifying question. As they put the PERT teams together, would a user of RapidAI in neuro be part of that PERT team?
Adam Elsesser
executiveNo, not likely. But if the hospital already has the system installed, having another module is, I think, a different psychological thing than a brand-new vendor going through all the IT qualifications and stuff that happens. So I think it's a little bit...
William Plovanic
analystIt's easier to sell an add-on than it is for the first time, that's for sure. Neurovasc -- let's switch over to neurovascular. I mean that's the roots of Penumbra. Last year was a challenging year, especially the COVID dynamics. Just talk about what you're seeing today macro in that market and then specifically for you.
Adam Elsesser
executiveYes. Neuro continues to evolve. We went from having 4, 5 key players in the field. Now there's a lot more -- I'd be honest, not to be disrespectful, I've sort of lost track of all the companies a little bit that are sort of in this space. The field to step back a touch is, we saw a notable decline in the heart of COVID last spring in stroke patients. It was well documented. That's coming back. Hard to know exactly given the data sources out there. Has it come all the way back? I think so. That's most people's perception and in certain cases, it's growing. But there's a lot of energy at the recent SNIS meeting, which is the first in-person medical conference I've been to since the pandemic. There was a lot of energy. People are ready to get back out in the community, sort of get talking to their -- the services to sort of be part of driving stroke growth again. So that made me feel a lot of confidence that the field is alive and going. As it relates to our place in it and our products, obviously, with the recall of Xtra Flex, we lost share as people tried other folks' products. With the launch of RED 62 and now 68 and the newest -- the final catheter in that series coming this quarter, I have a lot of confidence. People are ready for our technology again. I think those products will be just what they're looking for. No one is happy with other -- people use other people's stuff. But there's not one that's like, "Oh, my God, this is the greatest one ever." And so for that reason, I think we have a lot of confidence that we can do pretty well in the back half of this year. And it's great to -- and again, I'm so proud of our team for the -- just the ability to constantly make changes and adapt and develop products that I think will be really good. So just at the most core level, we're pretty excited about that. And then we'll wait and see as things develop with our product that I put the name out there on our earnings call, Thunderbolt. Again, the goal is really simple, which is we want to be able to get all the clot out in as many patients as possible, as fast as possible. And that's not true across all boards. Stroke cases still sometimes are hard. They're challenging. You don't always get all the clot out. And I think we can make a big difference and sort of -- sort of reset the thinking in this field in a way that can drive even more growth. If it's easier, if it's more democratized, it's likely that we'll see even more growth. So I'm pretty optimistic right now about how not only the business itself and stroke will go, but our place in that business.
William Plovanic
analystLet's transition to the international. It says here it's 25%, 30% of your revenues. Japan is no longer a headwind. You got China is a driver. How should we think about -- like is this a one-country driver? Is this -- I know you're in multiple countries. But how should we -- if you think about the drivers and kind of the biggest opportunity, where do you think you're going to put the most time and effort?
Adam Elsesser
executiveYes. I think there's a few regions that are more immediate. Our European business has always been good. Can we make it even better? We don't have really the core of our peripheral drivers there yet. Lightning and Indigo aren't really an active part of that business. I think that's coming. So I think that could really reignite some of the excitement and growth, obviously, and the same thing with the RED series. So Europe, I think, is going to see some renewed focus and energy. And then, obviously, we've talked about our China business model and our great partnership there. I think there's room to go, that started out as a more limited trial with a couple of our older stroke products. I think there's a lot of room there. And then our business in Japan last year was tough. This year, we're sort of back on track and that partnership is feeling particularly strong. And I think we're going to see some additional growth there. The other parts of the market, Latin America and other parts of Asia Pacific, are still good opportunities, but you can't do it all simultaneously. So those are the more focused areas. But even in the other ones, we'll have some growth to it.
William Plovanic
analystHow should investors think about -- we've seen the growth come back and the earnings are -- it's like you're making money, but you're not making a ton of money. And how do you think about forward? Is it more about continued -- because the opportunity is so big, continue driving top line growth and -- just as long as you're not burning cash or a lot of cash, we're fine. How do you think about that?
Adam Elsesser
executiveYes. Look, you want to balance it to some degree, but the way I look at it is pretty simple. As long as there are significant areas where we can help an awful lot of people and we think there's a decent shot of our success, we should take that as long as it's financially responsible. And that's how we've always run the business. And I think we'll continue to do that. What those metrics change as we get bigger, obviously, but so do the opportunities. And maybe it's a perfect way to sort of end. But September 21, you'll hear about that, because that's an opportunity that has the ability to help so many people measured in the millions and millions and millions of people, which is extraordinary, who gets the privilege of having a real shot at helping that many people. Like that's an important thing and to do it with a type of dynamic where there's a lot of people rooting, the whole field sort of wants this to happen in the sort of our health care world, I think it puts us in a really good spot. And I think it's going to -- if it's successful, be obviously another significant part of our business in the future years. So that's how we think about it. Let's spend what's necessary in a responsible way in order to help as many people as possible.
William Plovanic
analystI think that's a perfect point to end this. I want to thank you for your time, Adam. Again, this is Canaccord Genuity 2021 Growth Conference, and we just had a conversation with Adam Elsesser of Penumbra. Thanks, Adam.
Adam Elsesser
executiveThanks. Appreciate it, Bill.
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