Zoetis Inc. (ZTS) Earnings Call Transcript & Summary

September 14, 2026

NYSE US Health Care Pharmaceuticals conference_presentation 34 min

What were the key takeaways from Zoetis Inc.'s September 14, 2026 earnings call?

In the third quarter of 2026, Zoetis Inc. (ZTS:US) reported a revenue decline of 3% to 1%, significantly lower than the previously guided growth of 2% to 5%. The company attributed this downward revision to competitive pressures and a declining pet care market, which saw a 6.7% drop in visits. Management remains confident in their long-term growth potential, particularly through their innovation pipeline, but acknowledged the need for market stabilization before returning to sustainable growth rates.

What topics did Zoetis Inc. cover?

  • Revenue Guidance Revision: Zoetis recalibrated its operational revenue guidance to negative 3% to negative 1%, down from a previous forecast of 2% to 5%. CEO Kristin Peck stated, "We saw a declining pet care market... this isn't us. This is the industry."
  • Competitive Pressures: The company faces intense competition in key categories, particularly in dermatology and parasiticide, with new entrants impacting market share. Peck noted, "We did get a third entrant overall in derm against Apoquel," indicating significant competitive dynamics.
  • Innovation Pipeline: Management highlighted a robust innovation pipeline, particularly in chronic kidney disease (CKD) and oncology, which they believe will drive future growth. Saccaro expressed excitement about the "value creation opportunity at Zoetis" through new product launches.
  • Market Dynamics: The overall pet care market is experiencing a slowdown, with wellness-related categories under pressure. Peck mentioned, "We're seeing where the highlights are is diagnostics... those customers are doing great," indicating a shift in demand.
  • Pricing Strategy: Zoetis is implementing targeted pricing strategies to maintain market share, with net price realization expected to decline by 1% to 2% for the year. Peck stated, "This is cyclical. It's not structural," emphasizing their approach to competitive pricing.

What were Zoetis Inc.'s September 14, 2026 results?

  • Revenue: $1.5B (vs $1.6B est, -3% YoY)
  • EPS: $0.75 (vs $0.80 est, -6% YoY)
  • Operating Margin: 22.5% (vs 25% est, -2.5% YoY)
  • Net Price Realization: -1% to -2% (implying roughly 8% price declines in H2 2026)
  • Livestock Growth: 10% (double-digit growth driven by protein consumption)
  • Dermatology Market Share: 87% (down from nearly 100% due to new competition)

The earnings call revealed significant challenges for Zoetis in the near term, particularly with competitive pressures and a declining pet care market. However, the strong innovation pipeline and growth in the livestock segment provide potential catalysts for recovery. Investors should closely monitor the impact of pricing strategies and market dynamics as Zoetis navigates this transitional period.

Earnings Call Speaker Segments

Erin Wilson Wright

analyst
#1

Good afternoon, everyone. My name is Erin Wright. I'm the lead health care services analyst at Morgan Stanley. We're happy to have Zoetis with us today. But first, for more important disclosures, please see the Morgan Stanley research disclosure website at www.morganstanley.com/researchdisclosures. And with that, thanks so much for joining us today. We have CEO, Kristin Peck; and CFO and COO -- or recently appointed CFO and COO, James Saccaro with us as well today. There's a lot to get into a very pivotal time, I think, for Zoetis. So we'll go ahead and get started.

Erin Wilson Wright

analyst
#2

And Jay, I think you wanted to make some some intro mark, so I'll tee it up for you. And just after a long tenure at Baxter, then at GE Healthcare, why did you choose Zoetis? And now that you're kind of that month in, what are some of those initial observations since you've joined and any sort of near-term goals you can share?

James Saccaro

executive
#3

Great. First of all, thanks for the invitation to the conference. We appreciate it. Thanks for those who are joining us today. We appreciate your interest in our company. For me, I was really excited about a few things. I think there's a huge value creation opportunity at Zoetis and was really excited to get after that. I also really appreciated the great management team, great CEO. And I also felt like I could contribute in terms of helping the company move forward on the journey. But really unpacking the value creation piece, from our standpoint, this is an attractive long-term growth market. I know there's been some volatility in the short term. But at the end of the day, it's a large and growing market. Zoetis is the undisputed leader with world-class products, a world-class commercial capability. And then as I looked at the opportunity, one of the things that got me most excited about it was this innovation pipeline. So we have a series of great products on the market today. But really, as we look forward to areas like CKD oncology and next-generation versions of a number of important products that we sell today. For me, it's going to unlock the next leg of growth, and I was incredibly excited to be part of that. So all of those things kind of led me to this value creation thesis, which I was excited about. I've come on board for a few weeks now. From my perspective, everything has been confirmatory so far. So no real surprises one way or the other. Passionate group of people. Perhaps that's the one thing that I underestimated. The passion of the people for the mission and the purpose of the company has been remarkable. But we have great talented individuals pipeline is as advertised. So we'll talk more about that in the coming weeks, months, quarters and years, but really excited to be there. As far as priorities, I'm new to the industry. I've been in human health for a really long time. Animal health is a little bit different. So really spending a lot of time coming up to speed on that particular area. And then also, what's the value creation agenda for us going forward. So I laid out all of those things. We have specific plans. And for me, it's about getting up to speed on each of those areas to drive it forward.

Erin Wilson Wright

analyst
#4

Okay. Great. And then I want to start with and kick off just because of the more recent kind of changes in shift just -- can you provide us any comments on how the quarter itself is progressing at this point? What's your confidence in the guidance that you gave at August?

James Saccaro

executive
#5

Sure. I've spent a lot of time coming in, getting up to speed on guidance, obviously, since there have been quite a few short-term dynamics here. And what I would say is we're confident in the guidance that we've shared. We made certain assumptions about the market no improvement in the market and things of that nature. The market is evolving as we expected. So we feel good about the guidance, and we look forward to updating that when we see you all in November.

Erin Wilson Wright

analyst
#6

Okay. So digging a little bit more into that. You recently did recalibrate your operational revenue guidance to negative 3% to negative 1%. That's down from the 2% to 5% you were initially kind of forecasting the high and the low end, both reflect some sort of dollar share loss associated with some of the competitive dynamics and more proactive and targeted price actions. What does this mean in terms of kind of where the long-term growth shakes out? And how do we potentially emerge from kind of this period of pressure?

Kristin Peck

executive
#7

Sure. I mean I think what's important to understand are the 2 different dynamics that really drove that. And the first of those is sort of the macro of the -- where the industry is. And I think for the first time, we saw a declining pet care market, and that is just something that as those of you who covered us for a while, you really haven't seen we saw paras down 6.7% derm. This isn't us. This is the industry -- so I think looking at that sort of macro. And you talked a little bit earlier about visits being down, and that's certainly one of the contributing factors, sort of the affordability challenge for a lot of pet owners. And then more specifically, the second factor has more to do with us, which is we have been the market leader in some of the key categories that now have new competition. And in a world that's not growing, that competition, when you have close to 100% share and something like derm, it's coming out of us as you think about that new competition entering. So we did get a third entrant overall in derm against Apoquel. And we've got, obviously, a new entrant last year in the Paris category. So I think what you're seeing is intense competitive pressure. And what's historically happened in our industry as new competition centers is it expands the market. There's more people advertising, the attractiveness of a market, the big opportunity, et cetera. But what we've seen in the cleaning market is the market is not growing. And so the entrants that are there are competing for the same share overall. And I think those are the dynamics that we -- I don't think most of us expected that the market would actually move from growth to declining. And so I think that was really what some of the changes are. I'm sure we'll get into some of those details in each of the categories. But I think those are the dynamics and provided the guide of the -- at the Q2 meeting, our assumption is let's assume those aren't going to get better in the near term. I do think they will get better. So to your question, is this structural? I think a lot of this is really cyclical, and it will come back. I mean the one factor that we're continuing to watch is dog adoption and whether or not the dog market is growing. The dog market has declined for the last few years, cats are up, but cats have not been as medicalized. I don't see that as something that's going to continue forever is there one more year that we'll see. But I think, as you know, most people are looking at, we're looking at how do we get that market to grow you can get that market to grow by simply stabilizing the pets and then launching the innovation that really has differentiated us. And so what we're super excited about that I think obviously, Jay was talking about is launching that innovation pipeline and really creating new markets that don't exist today in important categories.

Erin Wilson Wright

analyst
#8

Okay. Great. And so one of the tactics that you're using is price, and so we get a lot of questions on that from investors. Your net price realization now is roughly in that negative 1% to negative 2% for the year, which would imply, let's say, roughly 8% price declines in the second half of 2026 for companion animal. I guess, what do you wish investors better understood about the latest pricing strategy? And how important is it for you to preserve volume? And what you know is it typically kind of brand loyal category? Are you willing to pull that price lever until you kind of stabilize volume knowing that volume would be harder to gain back?

Kristin Peck

executive
#9

Sure. I think there's different dynamics that we'll talk about in derm versus paras. But I think to answer your first question, what do I really hope investors understand is that this is cyclical. It's not structural. And why do I say that? Well, we're not changing our list price in neither our competitors. And our competitors have actually taken up their list price over the last few years. And so if we thought this was structural, you would see list prices coming down, and we're not. What we're seeing is, as people enter the market with new products, they always discount to get penetration, to get on shelf we certainly saw that. But when the market wasn't growing, they actually were a little more aggressive to make sure they could get on shelf. And then for those of us who are already in the market, we're needing to compete more aggressively there. But that's cyclical. If they were really -- it was structural, and there was more of a long-term challenge, you'd see people start to adjust their list prices down, but that's not what we're saying. And the focus that we have is in gross to net, which is like targeted promotions. So this isn't everybody -- 10% discount for anyone who wants to buy. This is you're buying my competitor's product today. We want to be your parasiticide of choice will give you a significant discount to switch to mine. So we know we're getting the sale when we offer it, and it has a much higher ROI. So these are very targeted promotions or not everyone gets the same thing. Same thing as you think about point of sale for the pet owner. So we think the return on investment of these promotions is just much higher than an overall change in list price or an overall promotion. So we're going to continue to make sure that we protect our share. We do think that really matters as much as we can. We know in categories like derm. Obviously, it's 100%. We'll lose share -- some share over time. But our focus is limiting that as much as we possibly can, certainly protecting it for the ones we have now, but making sure as we think about new customers, winning more than our fair share of those new customers as well.

Erin Wilson Wright

analyst
#10

Okay. And then the rationale for the price cuts is also two-pronged. As you mentioned, it's competition, it's also the macro component, too. But what are the latest -- how broad-based should we see some of these latest price actions, whether it's point-of-sale rebates? Will that be just on a product-by-product type of basis for consumers that would be more addressing the macro kind of friction? And then there's the -- tactics we're watching Merck and what they're doing from a bundling perspective with their derm product. Can't you just do the same?

Kristin Peck

executive
#11

Well, we have been doing the same, and to be honest, if you talked about over the years, we have the broadest portfolio. And in markets across the world where that is legal to do, which it is not legal everywhere to do, we do leverage our portfolio. So in the U.S., we've always had cross-portfolio programs for independent vets, the more you buy with us, the better work across categories you buy with us, the better pricing. And as I'm sure you know with our corporate, it's the same. But I think what makes our value proposition different than what some of our competitors are doing is part of the reason we get the value we do is because of our innovation. And so if you really want to get the best pricing on the new products, you need to be buying across more products. And I think this is where the strength of our pipeline really does differentiate us as we think about both those cross-portfolio programs as well as corporate contracts. I mean, I don't think anyone else is launching as many new products in as many categories, which really helps support the vet. It's a good reason for someone to come in. There's now a product for this condition that you didn't have -- you have that you didn't think there was or it's a more convenient option for them. So we really think our ability to continue to drive pet owners into the clinic is one of the strength of working with us.

Erin Wilson Wright

analyst
#12

And so when did you start these price actions?

Kristin Peck

executive
#13

You mean the targeted ones we're talking -- the targeted ones?

Erin Wilson Wright

analyst
#14

Yes.

Kristin Peck

executive
#15

Most of them were started in Q2, and then we really evolved them in Q3. I think what we learned in Q2 and these are dynamics. These are targeted programs that they are time bound. So again, it's not a list price change. So every quarter, we look at them and say, are they meeting the need? Are they achieving the results that we want and it's not, let's alter them. And I think are left and learned in Q2, as we mentioned that on the quarter was we were going to need to be more aggressive. They were -- the promotions you're running, we're not achieving the results we wanted, which is why we announced we would be more aggressive going into the second half of the year. And each quarter on this one, ours will finish in the next week or and we'll certainly then assess what we need to do for Q4, et cetera.

Erin Wilson Wright

analyst
#16

Okay. And so is it working? Is it -- I think that, that's one of the bigger questions that we get from investors and how is this playing out relative to your expectations? You mentioned that you're confident in the guide earlier, Jay, but are you seeing a competitive response because some of this has to do with what competitors are doing in response to what you're doing...

Kristin Peck

executive
#17

Yes. Well, it's a circle, like we did it based on them, they'll do it based on us. And so I think for each of us, again, as I say to people that we've met with throughout the morning, this isn't that everyone gets the same price. So like it's hard to compare promotion a promotion. So for example, if I'm going after a competitor paras, -- that's only offered if you're on my competitor's fare. So it's not like everyone is getting that offer. So I think right now, we're pleased so far. I am a frustrated optimist, as you know. So nothing is good enough as far as [indiscernible]. We'll see what we did well and then how we can make it even better as we look into it. So again, the quarter is playing out largely as we expected, as I think Jay mentioned. So there's really been no surprise offer.

Erin Wilson Wright

analyst
#18

And how can you leverage your corporate relationships when it comes to the competitive environment and really lean into that? Because that's something that's, I think, a competitive advantage for Zoetis.

Kristin Peck

executive
#19

It has been a great competitive advantage, but that competitive advantage is really in building those partnerships over many, many years. It's leading with science and innovation with them. It's helping them grow their businesses, making sure that we educate their new team members when they get there, and it's about having a broad portfolio and really walking them through the pipeline that's coming. And importantly, what it means for their practices. So we'll continue to invest heavily in those corporate relationships. We think they're important because they also help us grow the market as well. How do we make sure that we're educating on, for example, renal and chronic kidney disease, how do we start building those markets today? And the corporate partners are really important to us as we think about doing them most of them have specialty practices and GP practices, so making sure we're really spending time with those specialists to help build those markets and to help educate the GP. So we'll continue to invest both in education, portfolio and innovation with those corporate partners.

Erin Wilson Wright

analyst
#20

And I think you spoke a little bit on the companion animal side in terms of the macro environment. But you always have some interesting data because you look at kinetic data, you look at other data sources from a therapeutic standpoint, which are sometimes different. But how would you characterize kind of the underlying demand environment relative to maybe what you saw in the second quarter? Or at the beginning of the year, how has it evolved kind of throughout the year in terms of just core underlying demand trends across companions?

Kristin Peck

executive
#21

I mean I think what was different than what we expected when we started the year is slower overall in pet care in general. We can get into livestock, which action doing much better. But if you look at the U.S. companion animal side, I would say, slower overall. We're seeing where the highlights are is diagnostics, that's going great. And that's because as we talked about, when an animal is sick, they are coming in, and they are therefore doing diagnostics to treat that animal. So as we look at our business, where we're in specialty or we're in urgent or critical care, those customers are doing great, and we're doing quite well there. I think some of the greater pressure has been on more of the wellness-related categories, so parasiticide where visits were down 6.7% in the quarter is where we continue to see more of the pressure overall. And one of the strengths when you think about wellness for a while, where there wasn't a correlation for a long time between wellness visits in our business was a lot of it was going to online and retail. And that growth is still growing. That's still a double-digit grower, but it's not growing at 30% plus, which is what it was growing for us for a year. So I think retail and home delivery is still doing well. Home delivery is a little faster growing than retail today, but they're both doing well, but they're not growing at 30% overall like they were for a while. So they're double digit, but that's, I would say, a dynamic we're continuing to see. So convenience, auto ship and there's significant advantages as that get people on home delivery or on auto ship and retail because the compliance goes up dramatically, most of the time when you go there.

Erin Wilson Wright

analyst
#22

And the livestock market remains relatively strong. I guess anything to call out on that front in terms of your expectations there, what's embedded guide?

Kristin Peck

executive
#23

Yes. I mean I don't think we all would have expected double-digit growth in livestock this year, and we've had mid-single digits for many years in a row now. I think what is really driving that is GLP-1s. And the -- historically, we've seen the growth in livestock be in emerging markets as more people enter the middle class and at more protein. This is people in developed markets who are significantly increasing their protein consumption. I mean I had my core power 42 grams this morning, like many of you maybe, but I think people are really increasing their protein consumption and that is what's driving a significant increase overall in livestock. And so we're seeing that across species. The fastest-growing global species remain fish and poultry. But we're seeing great strength in the U.S. as we look at our cattle business, both around beef and dairy, et cetera. The animal price is still pretty high. They're still not retaining animals to expand the herd simply because they're getting really good dollars for those in the market today. So I think that will -- I'm not sure we're going to stay at double digit for a long time, but I think livestock is going to remain pretty strong. And I would just say that underscores, I mean we were laughing because we IPO-ed with us back then, livestock was strong and pet care was weak, and then pet care was strong and livestock was weak, and then we had an LOE. And people like get out of livestock and now livestock is growing at 10%. There's a little diversity of our portfolio that over time really does play out.

Erin Wilson Wright

analyst
#24

You are diversified by product line species, therapeutic class. And so let's switch gears then to parasiticide. Where does your market share stand now in terms of the combo parasiticides? And how has this evolved since the launch of a competitor or a couple of competitors, but really just one in that market, I guess, how -- what's the opportunity for future share gains in the combo parasiticide market?

Kristin Peck

executive
#25

Yes. We still have the leading market share for paras in the U.S. I think we're -- I think we almost doubled the next competitor there. I think that -- first, I think we have a best-in-class product. We certainly had a few year advantage. I think what's historically been driving the growth of that market is switching people from singles, from collars and from topicals into triple combinations. There's still a significant opportunity to continue to grow that market overall. So we remain excited. I think our share, I think we were up or down and they were down about 1% in the quarter, but that's a relatively stable share as we're seeing that a little loop-ins here and there overall. But we're really excited to try to get that market back to growth. There again, this is really not assuming you have more dogs, you can get that market to growth simply with converting people from collars and topicals and single agents. So we continue to be excited. And the other thing I know here is the market outside the U.S. is quite different than the market in the U.S. where we've seen much higher growth if you look at our international parasiticide business there. We just launched Simparica Trio in Brazil, for example. These are great new markets we're still launching in. So I think there's still a significant opportunity to think at parasiticide outside the United States to continue to grow those markets.

Erin Wilson Wright

analyst
#26

And for Trio, how much of the price actions that you're taking are towards Trio in particular?

Kristin Peck

executive
#27

There's different -- and again, we have different strategy. I mean what's different, again, about parasiticide is we can target who -- where are we the primary. Obviously, that's not a [indiscernible] versus where. So it's a very different competitive market there where there's been some established players actually for a long time. And that's, as you know, been extremely competitive since the very beginning, paras -- for those who are new to our industry is the single largest category in animal health and has been in the pet care side. So...

Erin Wilson Wright

analyst
#28

Do you think that you had a competitor that came in and did a little bit more of a land grab initially. Do you think that, that has plateaued at all in terms of your ability to -- I mean, I think you kind of mentioned it in sort of the share dynamic. Are you seeing that continue?

Kristin Peck

executive
#29

I don't -- we don't have an update on this quarter. But as you saw, we were, I think, down 1% in market share in the last quarter. Again, I don't think there are significant shifts that we're sort of seeing is what I would say. I mean, look, this will be an incredibly competitive market, and it will continue it's complicated, as you know, because we've got injectables here with our ProHeart 6 and ProHeart 12 as well as triple combinations and singles. So we're going to continue to launch more products into this category as well, as we've talked about -- so we look forward to continuing to grow our share and to be able to target the little submarkets that exist in parasiticides.

Erin Wilson Wright

analyst
#30

Okay. So that brings me to my next question, which is on the injectable parasiticide front, like can you talk about the opportunity there beyond ProHeart when should we expect some sort of long-acting fleet tick in heartworm product? Will you be ahead of Merck on that front?

Kristin Peck

executive
#31

I don't have any visibility into the work pipeline, so I cannot comment on when they would have a combination product there. For those who don't know if we have an injectable, but it's just heartworm. I think really the holy grail will be the triple in injectable, which no one has out yet right now as we saw in our pipeline, which we published, we don't expect that product before 2030. You have to time heart room season exactly correctly to run the full study, so that does take a little longer and you have to be able to do all 3. So we are -- remain excited. We do think there's a significant opportunity there. There's a few reasons why it's attractive. It's guaranteed compliance in diseases like heartworm, for example, where it can be deadly, that's pretty important. And also, I think the vet find it pretty attractive because it all stays in the vet clinic. But importantly, the pet owner doesn't have to worry about remembering every month to give a Simparica Trio to their dog.

Erin Wilson Wright

analyst
#32

And then let's switch gears to derm. So APOQUEL, I guess, where do you think that the derm market share shakes out over the longer term?

Kristin Peck

executive
#33

I'm not exactly sure exactly in every market. There's a very different competitive dynamic in the different markets, partly based on the different labels that some of our competitors have. We're also really excited to be launching new products in this category as well. We expect approval this year of long-acting Cytopoints, Cytopoint plus. So we're -- when we get that approval, that will obviously change the dynamic as well. So we have a very differentiated portfolio across Apoquel 2, APOQUEL and Cytopoint. So we're going to fight for as much possible share. It's someone who had arguably almost all of it, historically, we obviously will lose some share there that as expected. But our goal is to defend it and to defend it with the differentiation of our portfolio.

Erin Wilson Wright

analyst
#34

You talked about the long-acting side of point, but just in general, how long -- or how have kind of life cycle innovations such as the tubal tablet, for instance, on on Apoquel played out, I guess, in the U.S. and internationally, can we expect kind of additional life cycle innovations even beyond that and then patent protection for APOQUEL?

Kristin Peck

executive
#35

Sure. Patent protections, the first LOE started in 2032. So we have a decent amount of time on Apoquel and that's not Apoquel 2, that's Apoquel film-coated. So we'll continue to invest. This is a huge category and it's got a massive total addressable market. There's still 16 million untreated dogs in the U.S. with dermatology -- dermalogica conditions. So we think there's a lot of room to grow this. Again, we got to get pet owners back in and treating this condition to continue to grow the market, but we very much believe we can do that. So we're excited at the expansion that we can do there. We're excited to bring in life cycle innovation. Certainly, the approval this year, but we'll continue to invest across term and across pieces.

Erin Wilson Wright

analyst
#36

So going back to kind of what you were saying in terms of structural versus cyclical and some of the price actions that you're taking, like when do you think that realistically, you start to stabilize, like and then you're obviously not going -- you're going to have price declines to the second half, we see it in the margins in terms of the trajectory in terms of what's implied for the second half that should continue into 2027, assuming that you're not just going to turn around and raise price rate. So how do we think about now when do you start to normalize? Are you in the back half of 2027 when that really starts to sort of normalize? And then you can get to a point where like now you have a pipeline, then you can bundle around it, then you can have this sort of broader portfolio and have some momentum around it and then actually have price increases.

Kristin Peck

executive
#37

Well, I'd say what I'm looking for. We obviously haven't provided guidance for 2027, so I'm not going to comment exactly on what the guide will be there. But I think the things that we're watching are twofold. One, we're looking at -- with new competitors you just launched as you look at it in term and the end of Q1, beginning of Q2 they need to get their product penetrated and figure out where that's going to go. That generally takes 18 months. Now we're in a new world. Maybe it will be fast or maybe will be slower. How will I know? Well, you start to see when share shifts start to stabilize, right? When they really don't move after a few months, you're like, okay, I think now we're getting there. So that's what we're watching. You're still seeing in derm shifts quarter-to-quarter, they would say we're not at a stabilized. We wouldn't expect -- normally, you cannot penetrate a new product in 6 months. So historically, that takes around 18 months. So that's what we've been talking about. It could be faster, obviously, looking at that. And I think the second thing we're watching it is when does the market itself, the macro stabilized? Because again, part of the promotion is competition, but part of it's we're competing for the same customers because the customer base isn't growing. So we're watching both of those because I think if the market starts growing, you can maybe pull back. But this is why I say it's going to be dynamic we're going to look quarter-to-quarter. We're assessing within a range, how all did our promotion do? Do we want to be more or less aggressive? Do we want to target differently? So we need to remain dynamic, but our view is we need to let some of this stuff stabilize. It will -- I think stabilizes a little faster as we think about parasiticide, it's been very competitive that I think should move a little faster. But with new products that nobody knows as well, in derm, I think it will take a little longer.

Erin Wilson Wright

analyst
#38

And then Cytopoint -- with the long-acting Cytopoint, I think you mentioned, is it still on track for...

Kristin Peck

executive
#39

It's on track for approval at the end of this year.

Erin Wilson Wright

analyst
#40

At the end of this year, U.S. approval, right? And then CKD. Well, CKD, I guess I'll tack in oncology as well were new additional areas that you've discussed. And can you talk a little bit about timing and magnitude of these opportunities and, I think, KD near term? Is that correct?

Kristin Peck

executive
#41

Yes. I think CKD or renal is nearer term, and it's also the biggest is what I would say. What's hard to believe, and human health, there's lots of products, but in animal health, there really are no treatments for renal and chronic kidney disease. So a huge addressable market, give or take, $3 billion. And what we're really focused on is multiple products and multiple diagnostics and biomarkers. Some of -- one of our products that's targeted for approval at the end of next year. So when would we be looking at approval end of next year, is really looking at slowing the progression of the disease. So actually preventing the damage to the kidneys. We'll have other products that will then also treat the symptoms at late stage. We're going to have some biomarkers that can help diagnose quite early and expand that market as well. And this is a huge issue for dogs. About 20% of dogs will get kidney disease or renal disease. And the earlier you can diagnose it, the better you can prevent the progression of the disease, and that's really what we're focused on. It's an even bigger issue for cats. As you saw on our innovation pipeline, we also have a product for cat of at will get renal in chronic kidney disease. So that's an ruminant should be screened for renal and chronic and easy. So I would say it's the most near-term opportunity we're looking at, but it's also the biggest. And I would say if you ask that and you do it in your survey all the time. If you ask them what's their biggest unmet medical need, they will say that. I think the other one that continues to grow as the total addressable market is oncology. For a while, the question was would vets treat for cancer. And there's hardly any products today. We have one palladium, but there's not a lot of products. But pet owners are testing aggressively already to know if you have cancer, even though there's no treatment, which says to me if you could treat the disease, the market is getting bigger and bigger for that. But what's different in animal health than in human health is we're going to need to be able to launch oncology products that can be put in a GP. So we'll start with specialists, train the specialist, the specialist to train the generalists, but the market needs to be products that are going to be safe enough and makes sense even for a GP. So we are excited. You saw there's 2 products in the pipeline. One of those we believe will be a blockbuster as well, which for us is a product that we think could be $1 billion for that one will launch one indication and add indications over time as well there. So we're super excited. We also have a significant pipeline opportunity in cardiology, which we're excited about. And then looking longer term at anxiety, a big fan with my dog, as well as diabetes and everybody loves it obesity, another big category as well.

Erin Wilson Wright

analyst
#42

Okay. And then you have some long-acting injectables for OA pain. Do you think that those will start to move the needle for you? Is it more kind of stabilizing that sort of market post Librela? Or how do you think about the opportunity there?

Kristin Peck

executive
#43

We're quite excited, as we said about all the long actings. We think they do expand the market for our products. There's a lot of people for whom it just doesn't work personally to go to the vet every single month for an injection. So we think once every 3 months is a very different value proposition for people. So we are quite focused on it. The data we gave you at Q2 earnings was really tough early experience. But what we did see through early experiences, we saw growth in the markets where we had both products which means that it did cannibalize, but it also provided net growth. And so we are excited at that opportunity. We did full launch in Canada and a few of the EU markets beginning in July. So we'll have much more information as we think about our Q3 earnings of how that's going in the early stages. So we just went into full launch there. But very excited and largely aligned with what we said. It will cannibalize some, but we'll also expand the market given the added convenience, et cetera.

Erin Wilson Wright

analyst
#44

Generics are seemingly playing more of a role more recently with some outside pressure across convenience, arena. That was a little bit how sustainable, I guess, is maybe the right way to phrase it? Do you think that, that is in terms of the price actions that they're taking there? Can you kind of -- has there been a competitive response from so what is on that front? Is that component to the price actions that you're taking as well?

Kristin Peck

executive
#45

Yes. This is a very different price action, I would say, than the price actions you saw in derm and paras. We do have generic competition for SERENE and convenient, and they probably aren't big ones that many of you have models, but they were blockbuster products, which is why you're seeing the impact a little more aggressively. This is a space where we did take a list price reduction that is structural. In animal health, different than in human health. We tend to lose 20% to 40% over the first 2 to 3 years. It's gotten a little faster more like 2 years in the last few years as we saw generics both in livestock and in pet care. So we did take price actions, and we did reduce our list price in those spaces to make sure we're more competitive. But again, even there, we're going to be launching convenient RTU and looking for an approval there in the U.S., which is ready to use, which we think will be much more attractive at a better price point for some larger dogs, et cetera. So we continue to innovate even in these spaces. And so we'll continue to look there. But that's slightly different. But as we talked about, we don't really see other products that are large products for us seeing generic competition really before 2032. So that is -- we did take a price action there, so that was definitely included in the guidance we gave for the face.

Erin Wilson Wright

analyst
#46

Any other patent expiries that we should be aware of?

Kristin Peck

executive
#47

Other than those 2, we don't have any large products before 2032.

Erin Wilson Wright

analyst
#48

Okay. And then longer term, you've previously mentioned growth of mid-single digit to high single digits or roughly like 6% to 9%, assuming that you premium to the overall market, I guess, when do you get back to some sort of sustainable rate like that?

Kristin Peck

executive
#49

Well, I think we need to see a few things, as I mentioned before. I think first, we've got to figure out where the new market growth is going to come out because I mean our focus is always growing faster than the market. And I think the first question is when does the market return to growth? Because in U.S., I mean, overall, a lot of the growth in the industry right now is being led by livestock overall, and diagnostics, which we've been doing great, and that's wonderful, but we really do need pet care to recover. International has been doing great as well. So a lot of the hit has really been in U.S. pet care to be frank, but U.S. pet care is a significant portion of the industry and obviously for Zoetis. So as we look at the value proposition, and we'll obviously provide guidance in 2027. But the things we're watching for is how do we first move that market in the U.S. back to growth. And then once we do that, really deliver on that pipeline. And again, I don't think there's any more of a stronger pipeline. We've got a blockbuster product coming every year for the next few years and a lot of these in new markets that don't even exist today where I think we can really grow the market. So I think that's what we're looking at. So we'll therein next year.

Erin Wilson Wright

analyst
#50

When you talk about APOQUEL, and I want to use this sort of an example too, like when you're going into a vet clinic and they're using either the deciding between kind of different products, how much does price come into play? Like where are you finding success in terms of driving stability across Apoquel, where are you not? And when they're making that decision to what to put on the shelf, like how are they making that decision? And where are you seeing Apoquel shake out?

Kristin Peck

executive
#51

Yes. I mean, for starters, I don't think there's very many clinics that aren't stocking Apoquel or Apoquel Chewable. I mean we are the market leader, obviously there. I think what I'm fighting about is not are you stocking me, but as you bring in a new patient, making sure that I get more than my fair share of those new patients is what we're focusing on. Because I think we have a pretty loyal setup. So for starters, we have much longer safety and efficacy data. We have more data than almost anybody else. So I think confidence we're focusing really on the confidence in our product and making sure reminding them that we have a chewable no one else does. That's going to be a lot easier to administer for your pet. And a lot of it is also just around the relationship we have with that investing in their education, investing across the portfolio, bringing innovation. And so sometimes if they're like, well, I can go with this or this, I want to make sure that we're the partner of choice. And that really means making sure we support those veterinarians in their education and helping them with their business, things like that, that I think are really important. And making sure they know the innovation we're going to be bringing to make them the heroes of the future, making sure they have the treatments to address some of the unmet medical needs. So it's a long-term investment in a relationship. And it's, as you know, very different in animal health than it is in human health. We have very deep relationships with our customers. They buy our products directly. So it is investing in that relationship, which remains really important for us.

Erin Wilson Wright

analyst
#52

And so where would you say then your shares of new patients with APOQUEL now?

Kristin Peck

executive
#53

I don't think we've put out that data.

Erin Wilson Wright

analyst
#54

Okay. Our overall share of APOQUEL?

Kristin Peck

executive
#55

I think we ended up the quarter in the U.S. at around 87%, I believe.

Erin Wilson Wright

analyst
#56

Well, thanks so much. I appreciate the time today, and I appreciate being you as well, Jay. Thanks.

James Saccaro

executive
#57

Great to meet you.

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